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ChemicalBook >> CAS DataBase List >>ACX-362E

ACX-362E

CAS No.
1275582-97-2
Chemical Name:
ACX-362E
Synonyms
ACX-362E;Ibezapolstat;2-[[(3,4-Dichlorophenyl)methyl]amino]-1,7-dihydro-7-[2-(4-morpholinyl)ethyl]-6H-purin-6-one;6H-Purin-6-one, 2-[[(3,4-dichlorophenyl)methyl]amino]-1,7-dihydro-7-[2-(4-morpholinyl)ethyl]-
CBNumber:
CB85821086
Molecular Formula:
C18H20Cl2N6O2
Molecular Weight:
423.3
MDL Number:
MFCD31568418
MOL File:
1275582-97-2.mol
Last updated:2025-04-17 18:22:24

ACX-362E Properties

Boiling point 663.2±65.0 °C(Predicted)
Density 1.56±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka 6.75±0.10(Predicted)
form Solid
color White to off-white
FDA UNII 5K543KNC5P

ACX-362E price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC D432225 2-[[(3,4-Dichlorophenyl)methyl]amino]-1,7-dihydro-7-[2-(4-morpholinyl)ethyl]-6H-purin-6-one 1275582-97-2 25mg $430 2021-12-16 Buy
Product number Packaging Price Buy
D432225 25mg $430 Buy

ACX-362E Chemical Properties,Uses,Production

Uses

2-[[(3,4-Dichlorophenyl)methyl]amino]-1,7-dihydro-7-[2-(4-morpholinyl)ethyl]-6H-purin-6-one is derived from 2,6-Dichloropurine (D435760), which is used in the synthesis of 2,6-Diamino-substituted purine derivatives as potential cardiomyogenes inducing agents.

in vivo

Ibezapolstat is poorly absorbed and apparently nontoxic in the hamster C. difficile-associated disease (CDAD) model (potential for achieving a high local concentration at the site of C. difficile infection in the colon)[3].
Ibezapolstat (50 mg/kg; p.o.; twice daily; for 3 days) shows strong anti-C. difficile properties in the hamster CDAD model[3].

Animal Model:Female golden Syrian hamsters (80-90 g), CDAD model[3]
Dosage:50 mg/kg
Administration:Oral administration, twice daily, for 3 days
Result:Completely protected C. difficile-infected animals for a period of up to 5 days.

ACX-362E Preparation Products And Raw materials

Raw materials

Preparation Products

ACX-362E Suppliers

Global( 13)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32275 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38664 58
TargetMol Chemicals Inc.
+8613564774135 zijue.cai@tsbiochem.com United States 19905 58
Shanghai Beckham Medical Technology Co., Ltd 021-13816613772 13816613772 huahero21@sina.com China 997 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9803 58
Shanghai Chaolan Chemical Technology Center 021-QQ:65489617 15618227136 Sales@ATKchemical.com China 9346 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9729 58
Shanghai Dexuan Pharmaceutical Technology Co., Ltd 1701086315 dexuanpharma@126.com China 9475 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24873 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9835 58

View Lastest Price from ACX-362E manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ibezapolstat pictures 2024-10-28 Ibezapolstat
1275582-97-2
US $142.00-916.00 / mg 10g TargetMol Chemicals Inc.
  • Ibezapolstat pictures
  • Ibezapolstat
    1275582-97-2
  • US $142.00-916.00 / mg
  • TargetMol Chemicals Inc.
ACX-362E 6H-Purin-6-one, 2-[[(3,4-dichlorophenyl)methyl]amino]-1,7-dihydro-7-[2-(4-morpholinyl)ethyl]- 2-[[(3,4-Dichlorophenyl)methyl]amino]-1,7-dihydro-7-[2-(4-morpholinyl)ethyl]-6H-purin-6-one Ibezapolstat 1275582-97-2