ChemicalBook >> CAS DataBase List >>ACX-362E
ACX-362E
- CAS No.
- 1275582-97-2
- Chemical Name:
- ACX-362E
- Synonyms
- ACX-362E;Ibezapolstat;2-[[(3,4-Dichlorophenyl)methyl]amino]-1,7-dihydro-7-[2-(4-morpholinyl)ethyl]-6H-purin-6-one;6H-Purin-6-one, 2-[[(3,4-dichlorophenyl)methyl]amino]-1,7-dihydro-7-[2-(4-morpholinyl)ethyl]-
- CBNumber:
- CB85821086
- Molecular Formula:
- C18H20Cl2N6O2
- Molecular Weight:
- 423.3
- MDL Number:
- MFCD31568418
- MOL File:
- 1275582-97-2.mol
Last updated:2025-04-17 18:22:24
Boiling point | 663.2±65.0 °C(Predicted) |
---|---|
Density | 1.56±0.1 g/cm3(Predicted) |
storage temp. | Store at -20°C |
solubility | Soluble in DMSO |
pka | 6.75±0.10(Predicted) |
form | Solid |
color | White to off-white |
FDA UNII | 5K543KNC5P |
ACX-362E Chemical Properties,Uses,Production
Uses
2-[[(3,4-Dichlorophenyl)methyl]amino]-1,7-dihydro-7-[2-(4-morpholinyl)ethyl]-6H-purin-6-one is derived from 2,6-Dichloropurine (D435760), which is used in the synthesis of 2,6-Diamino-substituted purine derivatives as potential cardiomyogenes inducing agents.
in vivo
Ibezapolstat is poorly absorbed and apparently nontoxic in the hamster C. difficile-associated disease (CDAD) model (potential for achieving a high local concentration at the site of C. difficile infection in the colon)[3].
Ibezapolstat (50 mg/kg; p.o.; twice daily; for 3 days) shows strong anti-C. difficile properties in the hamster CDAD model[3].
Animal Model: | Female golden Syrian hamsters (80-90 g), CDAD model[3] |
Dosage: | 50 mg/kg |
Administration: | Oral administration, twice daily, for 3 days |
Result: | Completely protected C. difficile-infected animals for a period of up to 5 days. |
ACX-362E Preparation Products And Raw materials
Raw materials
Preparation Products
ACX-362E Suppliers
Global( 13)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32275 | 58 |
TargetMol Chemicals Inc. | support@targetmol.com | United States | 38664 | 58 | |
TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19905 | 58 |
Shanghai Beckham Medical Technology Co., Ltd | 021-13816613772 13816613772 | huahero21@sina.com | China | 997 | 55 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
Shanghai Chaolan Chemical Technology Center | 021-QQ:65489617 15618227136 | Sales@ATKchemical.com | China | 9346 | 58 |
Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9729 | 58 |
Shanghai Dexuan Pharmaceutical Technology Co., Ltd | 1701086315 | dexuanpharma@126.com | China | 9475 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24873 | 58 |
RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9835 | 58 |
View Lastest Price from ACX-362E manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-10-28 | Ibezapolstat
1275582-97-2
|
US $142.00-916.00 / mg | 10g | TargetMol Chemicals Inc. |
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- Ibezapolstat
1275582-97-2
- US $142.00-916.00 / mg
- TargetMol Chemicals Inc.
ACX-362E
6H-Purin-6-one, 2-[[(3,4-dichlorophenyl)methyl]amino]-1,7-dihydro-7-[2-(4-morpholinyl)ethyl]-
2-[[(3,4-Dichlorophenyl)methyl]amino]-1,7-dihydro-7-[2-(4-morpholinyl)ethyl]-6H-purin-6-one
Ibezapolstat
1275582-97-2