天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

ChemicalBook >> CAS DataBase List >>Arbutamine Hydrochloride

Arbutamine Hydrochloride

CAS No.
125251-66-3
Chemical Name:
Arbutamine Hydrochloride
Synonyms
CBNumber:
CB83159851
Molecular Formula:
C18H24ClNO4
Molecular Weight:
353.84
MDL Number:
MFCD00902164
MOL File:
125251-66-3.mol
Last updated:2024-10-28 16:48:35

Arbutamine Hydrochloride Properties

Melting point 55-58°
alpha D23 -18.5° (in ethanol)
FDA UNII K0NF2CPJ7F

Arbutamine Hydrochloride price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation API0008189 ARBUTAMINE HYDROCHLORIDE 95.00% 125251-66-3 5MG $502.65 2021-12-16 Buy
Product number Packaging Price Buy
API0008189 5MG $502.65 Buy

Arbutamine Hydrochloride Chemical Properties,Uses,Production

Originator

Genesa,Genesa,UK

Manufacturing Process

(R)-Arbutamin was produced as follows: 89.3 mg of (-)-1-di(tbutyldimethylsiloxy) phenyl)-2-aminoethanol, 50.0 mg of 4-(4- methoxymethoxyphenyl)butanoic acid, diethylphosphorylcyanide, and triethylamine were dissolved in N,N-dimethylformamide at 0°C, reacted at room temperature, so as to obtain 108.6 mg (in a yield of 82%) of amide compound. The amide compound obtained was reduced lithium aluminium hydride in an ether solvent at reflux temperature, so as to quantitative obtain amine. And 55.6 mg of (R)-arbutamin which is intended compound was obtained by deprotecting the hydroxyl-protecting group of amine in a methanol-THF solvent at room temperature using hydrochloric acid. [α]D 25 = -17 (c 1.15, EtOH).
(-)-1-(Dibutyldimethylsiloxy)phenyl)-2-aminoethanol was obtained by a hydrogenization of (R)-1-(3,4-di(t-butyldimethylsiloxyphenyl)-2-nitroethanol on 10% Pd/C.
The last compound was prepared as follows: the hydroxyl groups of 3,4- dihydroxy-benzaldehyde was protected using t-butyldimethylsilylchloride (1). 100 mg (0.26 mmol) of 3,4-di(t-butyl-methylsiloxy)benzaldehyde was dissolved in 1 ml tetrahydrofurane under atmosphere of argon at -40°C, and 0.30 ml of metal complex from (S)-6,6'-bis(triethylsilylethynyl)-1,1-dihydroxy- 2,2'-binaphtalene (2) mixed with a solution of n-butyllitium in hexane.After stirring for 30 minutes, 79.4 mg (1.3 mmol) of nitromethane was added dropwise to the mixture. After 67 hour reaction time, 2 ml of 1 N aqueous solution of hydrochloric acid added to stop the reaction. Product was extracted with 50 ml ethyl acetate, dehydrated with anhydrous sodium sulfate and concentrated within evaporator followed by silica gel chromatography (nhexane/ acetone = 10/1), after which (R)-1-(3,4-di(t-butyldimethylsiloxy) phenyl)-2-nitroethanol with an optical purity of 92% e.e. was obtained in a yield of 93%.

Therapeutic Function

Cardiotonic

Arbutamine Hydrochloride Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
TargetMol Chemicals Inc.
+8613564774135 zijue.cai@tsbiochem.com United States 19885 58
Pharmacodia (Beijing) Co.,Ltd +86-400-851-9921 sales@pharmacodia.com China 2317 55
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19704 58

View Lastest Price from Arbutamine Hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Arbutamine hydrochloride pictures 2024-10-28 Arbutamine hydrochloride
125251-66-3
US $1520.00-1980.00 / mg 10g TargetMol Chemicals Inc.
125251-66-3