Immuno modulator-1
- CAS No.
- 2757469-20-6
- Chemical Name:
- Immuno modulator-1
- Synonyms
- Immuno modulator-1
- CBNumber:
- CB814271629
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Immuno modulator-1 Chemical Properties,Uses,Production
Uses
Immuno modulator-1 (compound 22) inhibits TNFα and IL-2 secretion in human peripheral blood mononuclear cells (hPBMC), with IC50 values of 4.7 and 26 nM, respectively. Immuno modulator-1 shows hERG potassium channel blocking effect, with Inhibitory percentage of 20% at 3 μM[1].
in vivo
Immuno modulator-1 (compound 22) (1 mg/kg (IV), 5 mg/kg (PO); once) has an oral bioavailability of 30% in Male Sprague-Dawley rats[1].
| Animal Model: | Male Sprague-Dawley rats[1] | ||||||||||||||||||
| Dosage: | 1 mg/kg (IV), 5 mg/kg (PO) | ||||||||||||||||||
| Administration: | IV (2 mL/kg), PO (10 mL/kg); once (Pharmacokinetic Analysis) | ||||||||||||||||||
| Result: | Pharmacokinetic Parameters of Immuno modulator-1 in male Sprague-Dawley rats[1].
|
IC 50
IL-2
References
[1] Chen Xiangyang, et al. Heterocyclic immunomodulator. Patent, WO2022007659A1.
Immuno modulator-1 Preparation Products And Raw materials
Raw materials
Preparation Products
Immuno modulator-1 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19897 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19820 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
View Lastest Price from Immuno modulator-1 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-30 | Immuno modulator-1
2757469-20-6
|
US $0.00-0.00 / mg | 10g | TargetMol Chemicals Inc. |
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- Immuno modulator-1
2757469-20-6
- US $0.00-0.00 / mg
- TargetMol Chemicals Inc.