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ChemicalBook >> CAS DataBase List >>1H-Imidazole-5-carboxylic acid, 2-[[[(4-fluorophenyl)methyl][[4-(phenylmethoxy)phenyl]methyl]amino]methyl]-

1H-Imidazole-5-carboxylic acid, 2-[[[(4-fluorophenyl)methyl][[4-(phenylmethoxy)phenyl]methyl]amino]methyl]-

CAS No.
1382722-47-5
Chemical Name:
1H-Imidazole-5-carboxylic acid, 2-[[[(4-fluorophenyl)methyl][[4-(phenylmethoxy)phenyl]methyl]amino]methyl]-
Synonyms
MMPI-1154;2-(((4-(Benzyloxy)benzyl)(4-fluorobenzyl)amino)methyl)-1H-imidazole-5-carboxylic acid;1H-Imidazole-5-carboxylic acid, 2-[[[(4-fluorophenyl)methyl][[4-(phenylmethoxy)phenyl]methyl]amino]methyl]-
CBNumber:
CB78198405
Molecular Formula:
C26H24FN3O3
Molecular Weight:
445.49
MDL Number:
MFCD32693883
MOL File:
1382722-47-5.mol
Last updated:2025-04-18 09:52:45

1H-Imidazole-5-carboxylic acid, 2-[[[(4-fluorophenyl)methyl][[4-(phenylmethoxy)phenyl]methyl]amino]methyl]- Properties

Boiling point 675.1±55.0 °C(Predicted)
Density 1.308±0.06 g/cm3(Predicted)
pka 14.37±0.10(Predicted)
form Solid
color White to yellow

1H-Imidazole-5-carboxylic acid, 2-[[[(4-fluorophenyl)methyl][[4-(phenylmethoxy)phenyl]methyl]amino]methyl]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0068741 MMPI-1154 99.87% 1382722-47-5 5mg $300 2021-12-16 Buy
ChemScene CS-0068741 MMPI-1154 99.87% 1382722-47-5 10mg $500 2021-12-16 Buy
Product number Packaging Price Buy
CS-0068741 5mg $300 Buy
CS-0068741 10mg $500 Buy

1H-Imidazole-5-carboxylic acid, 2-[[[(4-fluorophenyl)methyl][[4-(phenylmethoxy)phenyl]methyl]amino]methyl]- Chemical Properties,Uses,Production

Uses

MMPI-1154 is a promising novel cardio-cytoprotective imidazole-carboxylic acid (ICA) MMP-2 inhibitor(IC50=6.6 μM) and can be used for the study of acute myocardial infarction. MMPI-1154 also inhibits the activity of MMP-13, MMP-1 and MMP-9 with IC50s of 1.8 μM,10 μM, and 13 μM, respectively[1].

IC 50

MMP-2: 6.6 μM (IC50); MMP-13: 1.8 μM (IC50); MMP-1: 10 μM (IC50); MMP-9: 13 μM (IC50)

References

[1] Péter Bencsik, et al. Development of Matrix Metalloproteinase-2 Inhibitors for Cardioprotection.Front Pharmacol. 2018 Apr 5;9:296. DOI:10.3389/fphar.2018.00296

1H-Imidazole-5-carboxylic acid, 2-[[[(4-fluorophenyl)methyl][[4-(phenylmethoxy)phenyl]methyl]amino]methyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Imidazole-5-carboxylic acid, 2-[[[(4-fluorophenyl)methyl][[4-(phenylmethoxy)phenyl]methyl]amino]methyl]- Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 62072 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9835 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19784 58
Biosynth Biological Technology (Suzhou) Co Ltd 51288865780 sales@biosynth.com China 233051 58
MMPI-1154 1H-Imidazole-5-carboxylic acid, 2-[[[(4-fluorophenyl)methyl][[4-(phenylmethoxy)phenyl]methyl]amino]methyl]- 2-(((4-(Benzyloxy)benzyl)(4-fluorobenzyl)amino)methyl)-1H-imidazole-5-carboxylic acid 1382722-47-5