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Cyclophilin inhibitor 1
- CAS No.
- 1509904-96-4
- Chemical Name:
- Cyclophilin inhibitor 1
- Synonyms
- Cyclophilin inhibitor 1;Spiro[20H-7,2-([1]butenoxyethaniminoethano[1,3]-endo-pyridazinomethaniminomethano)quinoline-11,5'-[1,3]dioxane]-12,15,18,25-tetrone, 21,22,23,24-tetrahydro-17,27-dimethyl-14-(1-methylethyl)-, (9E,14S,17S,21S,27R)-
- CBNumber:
- CB75821100
- Molecular Formula:
- C31H39N5O7
- Molecular Weight:
- 593.68
- MDL Number:
- MFCD32062752
- MOL File:
- 1509904-96-4.mol
Last updated:2025-04-18 09:52:43
Cyclophilin inhibitor 1 Chemical Properties,Uses,Production
Uses
Cyclophilin inhibitor 1 is a potent and orally bioavailable cyclophilin A inhibitor, with a Kd of 5 nM, shows effective anti-HCV activity, with an EC50 of 98 nM for HCV 2a[1].
IC 50
Cyclophilin A
References
[1] Mackman RL, et al. Discovery of a Potent and Orally Bioavailable Cyclophilin Inhibitor Derived from the Sanglifehrin Macrocycle. J Med Chem. 2018 Nov 8;61(21):9473-9499. DOI:10.1021/acs.jmedchem.8b00802
Cyclophilin inhibitor 1 Preparation Products And Raw materials
Raw materials
Preparation Products
Cyclophilin inhibitor 1 Suppliers
Global( 6)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32274 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9729 | 58 |
| Suzhou Haiben Pharmaceutical Co., Ltd | 14760821013 13564957716 | 1816280386@qq.com | China | 8045 | 58 |
| Nantong Hanfang Biotechnology Co. , Ltd. | hanfangpharma@126.com; 18616537568 | hanfangpharma@126.com | China | 29981 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 20017 | 58 |
| Adooq Bioscience LLC | 400-025-6535 | sales@adooq.cn | China | 18215 | 58 |
Cyclophilin inhibitor 1
Spiro[20H-7,2-([1]butenoxyethaniminoethano[1,3]-endo-pyridazinomethaniminomethano)quinoline-11,5'-[1,3]dioxane]-12,15,18,25-tetrone, 21,22,23,24-tetrahydro-17,27-dimethyl-14-(1-methylethyl)-, (9E,14S,17S,21S,27R)-
1509904-96-4
C31H39N5O7