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ChemicalBook >> CAS DataBase List >>12-PAHSA

12-PAHSA

CAS No.
1997286-65-3
Chemical Name:
12-PAHSA
Synonyms
12-PAHSA;12-[(1-oxohexadecyl)oxy]-octadecanoicacid;Octadecanoic acid, 12-[(1-oxohexadecyl)oxy]-
CBNumber:
CB74665697
Molecular Formula:
C34H66O4
Molecular Weight:
538.89
MDL Number:
MOL File:
1997286-65-3.mol
Last updated:2025-01-27 09:38:02

12-PAHSA Properties

Boiling point 614.3±28.0 °C(Predicted)
Density 0.916±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 20 mg/ml; DMSO: 15 mg/ml; Ethanol: 20 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
pka 4.78±0.10(Predicted)
form powder
UNSPSC Code 12352211
NACRES NA.25

SAFETY

Risk and Safety Statements

12-PAHSA price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 17107 12-PAHSA ≥95% 1997286-65-3 1mg $62 2024-03-01 Buy
Cayman Chemical 17107 12-PAHSA ≥95% 1997286-65-3 5mg $270 2024-03-01 Buy
Cayman Chemical 17107 12-PAHSA ≥95% 1997286-65-3 10mg $477 2024-03-01 Buy
AK Scientific 5310EA 12-Pahsa 1997286-65-3 10mg $629 2021-12-16 Buy
Product number Packaging Price Buy
17107 1mg $62 Buy
17107 5mg $270 Buy
17107 10mg $477 Buy
5310EA 10mg $629 Buy

12-PAHSA Chemical Properties,Uses,Production

Description

Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity.1 Structurally, these esters are comprised of a C-16 or C-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) linked to either a C-16 or C-18 hydroxy substituent. 12-PAHSA is a FAHFA in which palmitic acid is esterified at the 12th carbon of hydroxy stearic acid. Among the FAHFA family members, PAHSAs are the most abundant in the adipose tissue of glucose tolerant AG4OX mice, which overexpress the Glut4 glucose transporter specifically in adipose tissue.1 12-PAHSA is present at 2- to 3-fold higher levels in adipose tissue of AG4OX mice compared to wild type mice.1 Levels of 12-PAHSA are also higher in fasted wild-type mice compared to fed mice and are reduced upon high-fat diet-induced obesity in insulin-resistant mice.1

Definition

ChEBI: 12-PAHSA is a FAHFA obtained by formal condensation of the carboxy group of palmitic acid with the hydroxy group of 12-hydroxystearic acid. It has a role as an anti-inflammatory agent, a hypoglycemic agent and a human metabolite. It is a FAHFA and a long-chain fatty acid. It is functionally related to a hexadecanoic acid and an octadecanoic acid. It is a conjugate acid of a 12-PAHSA(1-).

References

1. Yore, M.M., Syed, I., Moraes-Vieira, P.M., et al. Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects Cell 159(2),318-332(2014).

12-PAHSA Preparation Products And Raw materials

Raw materials

Preparation Products

12-PAHSA Suppliers

Global( 27)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+17819995354 marketing@targetmol.com United States 32281 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8140 58
Changzhou Furuisi Biotechnology Co., Ltd 0519-85524369 3477467573@qq.com China 8617 58
Beijing Biocreative Technology Co., Ltd. 15522676233 3007606172@qq.com China 1248 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24890 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
Cayman Chemical Company 800-364-9897 sales@caymanchem.com China 6838 58
Merck KGaA 21-20338288 ordercn@merckgroup.com China 6394 58

View Lastest Price from 12-PAHSA manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
12-PAHSA pictures 2024-10-28 12-PAHSA
1997286-65-3
US $155.00-1190.00 / mg 10g TargetMol Chemicals Inc.
  • 12-PAHSA pictures
  • 12-PAHSA
    1997286-65-3
  • US $155.00-1190.00 / mg
  • TargetMol Chemicals Inc.
12-PAHSA Octadecanoic acid, 12-[(1-oxohexadecyl)oxy]- 12-[(1-oxohexadecyl)oxy]-octadecanoicacid 1997286-65-3