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ChemicalBook >> CAS DataBase List >>N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester)

N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester)

CAS No.
2093152-79-3
Chemical Name:
N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester)
Synonyms
SUN 52793;N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester)
CBNumber:
CB73373700
Molecular Formula:
C40H78N4O16
Molecular Weight:
871.08
MDL Number:
MFCD30723292
MOL File:
2093152-79-3.mol
Last updated:2025-04-18 09:52:40

N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) Properties

solubility Soluble in DMSO, DCM, DMF

N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
BroadPharm BP-23470 N-(Azido-PEG4)-N-bis(PEG4-t-butylester) 98% 2093152-79-3 100mg $320 2021-12-16 Buy
BroadPharm BP-23470 N-(Azido-PEG4)-N-bis(PEG4-t-butylester) 98% 2093152-79-3 250mg $580 2021-12-16 Buy
BroadPharm BP-23470 N-(Azido-PEG4)-N-bis(PEG4-t-butylester) 98% 2093152-79-3 500mg $980 2021-12-16 Buy
Product number Packaging Price Buy
BP-23470 100mg $320 Buy
BP-23470 250mg $580 Buy
BP-23470 500mg $980 Buy

N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) Chemical Properties,Uses,Production

Description

N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) is a 3-arm PEG reagentr consisting of a terminal azide group and two t-butyl esters. The azide group enables PEGylation via Click Chemistry. The t-buty ester groups can be hydrolyzed under mild acidic conditions.

Uses

N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) Preparation Products And Raw materials

Raw materials

Preparation Products

N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) Suppliers

Global( 15)Suppliers
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TargetMol Chemicals Inc.
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Aladdin Scientific
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Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; psaitong@jm-bio.com China 29772 58
N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) SUN 52793 2093152-79-3