N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester)
- CAS No.
- 2093152-79-3
- Chemical Name:
- N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester)
- Synonyms
- SUN 52793;N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester)
- CBNumber:
- CB73373700
- Molecular Formula:
- C40H78N4O16
- Molecular Weight:
- 871.08
- MDL Number:
- MFCD30723292
- MOL File:
- 2093152-79-3.mol
N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| BroadPharm | BP-23470 | N-(Azido-PEG4)-N-bis(PEG4-t-butylester) 98% | 2093152-79-3 | 100mg | $320 | 2021-12-16 | Buy |
| BroadPharm | BP-23470 | N-(Azido-PEG4)-N-bis(PEG4-t-butylester) 98% | 2093152-79-3 | 250mg | $580 | 2021-12-16 | Buy |
| BroadPharm | BP-23470 | N-(Azido-PEG4)-N-bis(PEG4-t-butylester) 98% | 2093152-79-3 | 500mg | $980 | 2021-12-16 | Buy |
N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) Chemical Properties,Uses,Production
Description
N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) is a 3-arm PEG reagentr consisting of a terminal azide group and two t-butyl esters. The azide group enables PEGylation via Click Chemistry. The t-buty ester groups can be hydrolyzed under mild acidic conditions.
Uses
N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) Preparation Products And Raw materials
Raw materials
Preparation Products
N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 32277 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-0431-80514535 19917294565 | et@chemextension.com | China | 3951 | 55 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4838 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85563444 18351873721 | purchase@synzest.com | China | 10434 | 58 |
| Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 | 3477467573@qq.com | China | 8617 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 3001317055@qq.com | China | 9993 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29772 | 58 |