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ChemicalBook >> CAS DataBase List >>Biotin-PEG4-Azide

Biotin-PEG4-Azide

CAS No.
1309649-57-7
Chemical Name:
Biotin-PEG4-Azide
Synonyms
(+)-Biotin-PEG4-CH2CH2N3;Biotin-PEG4-azide,Biotin-PEG4-N3;N-[2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethyl]biotinamide;N-(14-Azido-3,6,9,12-tetraoxatetradecyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide;Biotin-PEG4-CH2CH2N3/1H-Thieno[3,4-d]imidazole-4-pentanamide, N-(14-azido-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-, (3aS,4S,6aR)-
CBNumber:
CB73166962
Molecular Formula:
C20H36N6O6S
Molecular Weight:
488.60144
MDL Number:
MFCD27977501
MOL File:
1309649-57-7.mol
MSDS File:
SDS
Last updated:2025-04-18 09:52:39

Biotin-PEG4-Azide Properties

Melting point 102.0 to 106.0 °C
form powder to lump
color White to Light yellow

SAFETY

Risk and Safety Statements

HS Code  2934.99.9001

Biotin-PEG4-Azide price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical B5546 Biotin-PEG4-Azide >96.0%(HPLC) 1309649-57-7 100mg $475 2024-03-01 Buy
Chem-Impex 37489 Biotin-PEG4-azide,96%(HPLC) 96%(HPLC) 1309649-57-7 100MG $499.52 2021-12-16 Buy
AK Scientific J96951 Biotin-PEG4-azide 1309649-57-7 25mg $64 2021-12-16 Buy
BroadPharm BP-22119 Biotin-PEG4-azide 98% 1309649-57-7 100mg $280 2021-12-16 Buy
BroadPharm BP-22119 Biotin-PEG4-azide 98% 1309649-57-7 500mg $670 2021-12-16 Buy
Product number Packaging Price Buy
B5546 100mg $475 Buy
37489 100MG $499.52 Buy
J96951 25mg $64 Buy
BP-22119 100mg $280 Buy
BP-22119 500mg $670 Buy

Biotin-PEG4-Azide Chemical Properties,Uses,Production

Description

Biotin-PEG4-azide is a very useful biotinylation reagent that enable Click Chemistry reaction with alkyne, such as Propargyl, DBCO or BCN reagent to form a stable bond. PEG4 spacer increases aqueous solubility of the molecules conjugated to the biotin. It also helps to minimize steric hindrance involved with the binding to avidin molecules.

Uses

Biotin-PEG4-azide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Biotin-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521. DOI:10.1038/nchembio.2329

Biotin-PEG4-Azide Preparation Products And Raw materials

Raw materials

Preparation Products

Biotin-PEG4-Azide Suppliers

Global( 73)Suppliers
Supplier Tel Email Country ProdList Advantage
9i LLC 		+18039569191 MWan@NiNeiLab.com United States 418 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32222 58
Wuhan Borenpharm Co., Ltd 		027-65563561 18717150066 3207347307@qq.com CHINA 1238 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
Jilin Chinese Academy of Sciences-yanshen Technology 		+undefined18143011203 info@chemextension.com China 42056 58
Xian confluore Biological Technology Co., Ltd. 		+86-15680926068 +86-15680926068 1924344760@confluore.cn China 2996 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
Aladdin Scientific 		tp@aladdinsci.com United States 52924 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39927 58
Shaanxi Xinyan Bomei Biotechnology Co., Ltd. 029-86217788 13892832556 2440688701@qq.com China 1986 58

View Lastest Price from Biotin-PEG4-Azide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Biotin-PEG4-azide pictures 2024-11-19 Biotin-PEG4-azide
1309649-57-7
 US $66.00-166.00 / mg 99.09% 10g TargetMol Chemicals Inc.
Biotin-PEG4-azide pictures 2024-03-23 Biotin-PEG4-azide
1309649-57-7
 US $0.00 / mg 100mg >98.00% 100mg Xian confluore Biological Technology Co., Ltd.
  • Biotin-PEG4-azide pictures
  • Biotin-PEG4-azide
    1309649-57-7
  • US $0.00 / mg
  • >98.00%
  • Xian confluore Biological Technology Co., Ltd.

Biotin-PEG4-Azide Spectrum

N-(14-Azido-3,6,9,12-tetraoxatetradecyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide (+)-Biotin-PEG4-CH2CH2N3 Biotin-PEG4-azide,Biotin-PEG4-N3 N-[2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethyl]biotinamide Biotin-PEG4-CH2CH2N3/1H-Thieno[3,4-d]imidazole-4-pentanamide, N-(14-azido-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-, (3aS,4S,6aR)- 1309649-57-7 C20H36N6O6S peg