CpG ODN 10101
- CAS No.
- 1234402-77-7
- Chemical Name:
- CpG ODN 10101
- Synonyms
- ODN 10101;CpG ODN 10101
- CBNumber:
- CB714037972
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
CpG ODN 10101 Chemical Properties,Uses,Production
Uses
CpG ODN 10101, a synthetic oligodeoxynucleotide (ODN),? is a toll-like receptor 9 (TLR9) agonist. CpG ODN 10101 is a potent inducer of cytokine/chemokine expression ex vivo when used in combination with HH2(VQLRIRVAVIRA-NH2). CpG ODN 10101 induces IFN- secretion from dendritic cells (DCs) and stimulates B-cells.CpG ODN 10101 has antiviral and immunomodulatory properties that can influence chronic infection with HCV[1][2].
IC 50
TLR9
References
[1] Jason Kindrachuk, et al. A novel vaccine adjuvant comprised of a synthetic innate defence regulator peptide and CpG oligonucleotide links innate and adaptive immunity. Vaccine. 2009 Jul 23;27(34):4662-71. DOI:10.1016/j.vaccine.2009.05.094
[2] John G McHutchison, et al. Phase 1B, randomized, double-blind, dose-escalation trial of CPG 10101 in patients with chronic hepatitis C virus. Hepatology. 2007 Nov;46(5):1341-9. DOI:10.1002/hep.21773
CpG ODN 10101 Preparation Products And Raw materials
Raw materials
Preparation Products
CpG ODN 10101 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32239 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19820 | 58 |
| Sangon Biotech (Shanghai) Co.,Ltd. | 400-821-026 | Sales@sangon.com | China | 48813 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| Aladdin Scientific | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |
| Sangon Biotech (Shanghai) Co.,Ltd. | 58 |
View Lastest Price from CpG ODN 10101 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-07 | CpG ODN 10101
1234402-77-7
|
US $297.00-723.00 / mg | 94.06% | 10g | TargetMol Chemicals Inc. |
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- CpG ODN 10101
1234402-77-7
- US $297.00-723.00 / mg
- 94.06%
- TargetMol Chemicals Inc.