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ChemicalBook >> CAS DataBase List >>Drometrizole

Drometrizole

CAS No.
2440-22-4
Chemical Name:
Drometrizole
Synonyms
UV-P;TINUVIN P;2-(2-HYDROXY-5-METHYLPHENYL)BENZOTRIAZOLE;2-(2H-BENZOTRIAZOL-2-YL)-P-CRESOL;UV-71;Benazol II;RIASORB UV-P;Absorber UV-P;UV ABSORBER UV-P;2-(2H-Benzotriazol-2-yl)-p-kresol
CBNumber:
CB6426334
Molecular Formula:
C13H11N3O
Molecular Weight:
225.25
MDL Number:
MFCD00022903
MOL File:
2440-22-4.mol
MSDS File:
SDS
Last updated:2024-12-18 14:15:30

Drometrizole Properties

Melting point 125.5-129.5 °C(lit.)
Boiling point bp10 225°
Density 1.38
vapor pressure 0Pa at 20℃
refractive index 1.5600 (estimate)
Flash point 54°C
storage temp. 15-25°C
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 8.15±0.43(Predicted)
color Off-White to Pale Yellow
Water Solubility 173μg/L at 20℃
Merck 14,3447
Stability Hygroscopic
InChIKey MCPKSFINULVDNX-UHFFFAOYSA-N
LogP 4.2 at 25℃
CAS DataBase Reference 2440-22-4(CAS DataBase Reference)
Indirect Additives used in Food Contact Substances 2-(2'-HYDROXY-5'-METHYLPHENYL)BENZOTRIAZOLE
EWG's Food Scores 1-2
FDA UNII 5X93W9OFZL
NIST Chemistry Reference Phenol, 2-(2H-benzotriazol-2-yl)-4-methyl-(2440-22-4)
EPA Substance Registry System 2-(2H-Benzotriazol-2-yl)-p-cresol (2440-22-4)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS09
Signal word  Warning
Hazard statements  H317-H410
Precautionary statements  P261-P272-P273-P280-P302+P352-P333+P313
Hazard Codes  Xi
Risk Statements  36/37/38-53-43
Safety Statements  22-24/25-36/37
WGK Germany  1
RTECS  GO6860000
HS Code  29339900
Toxicity LD50 oral in mouse: 6500mg/kg
NFPA 704
1
2 0

Drometrizole price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich CRM96697 2-(2-Hydroxy-5-methylphenyl)benzotriazole certified reference material, TraceCERT? 2440-22-4 100MG $151 2024-03-01 Buy
Sigma-Aldrich 533203 2-(2-Hydroxy-5-methylphenyl)benzotriazole 97% 2440-22-4 25g $87.9 2024-03-01 Buy
Sigma-Aldrich 1228009 Drometrizole United States Pharmacopeia (USP) Reference Standard 2440-22-4 25mg $436 2024-03-01 Buy
TCI Chemical H0560 2-(2-Hydroxy-5-methylphenyl)benzotriazole >99.0%(HPLC)(T) 2440-22-4 25g $62 2024-03-01 Buy
TCI Chemical H0560 2-(2-Hydroxy-5-methylphenyl)benzotriazole >99.0%(HPLC)(T) 2440-22-4 500g $225 2024-03-01 Buy
Product number Packaging Price Buy
CRM96697 100MG $151 Buy
533203 25g $87.9 Buy
1228009 25mg $436 Buy
H0560 25g $62 Buy
H0560 500g $225 Buy

Drometrizole Chemical Properties,Uses,Production

Characterization

Drometrizole is an ultraviolet light absorber (UVA) of the hydroxyphenyl benzotriazole class, imparting good light stability to a wide variety of polymers.

Applications

Drometrizole provides ultraviolet protection in a wide variety of polymers including styrene homoand copolymers, engineering plastics such as polyesters and acrylic resins, polyvinyl chloride, and other halogen containing polymers and copolymers (e.g. vinylidenes), acetals and cellulose esters. Elastomers, adhesives, polycarbonate blends, polyurethanes, and some cellulose esters and epoxy materials also benefit from the use of Drometrizole.
   Drometrizole

Features/benefits

Drometrizole features a strong absorption of ultraviolet radiation in the 300-400 nm region. It also has a high degree of photostability over long periods of light exposure. The high absorbance combined with photostability and the ability to release absorbed energy in non sensitizing ways make Drometrizole an effective stabilizer against the effects of ultraviolet light.

Guidelines for use

The use levels of Drometrizole range between 0.10% and 0.50%, depending on substrate and performance requirements of the final application. Drometrizole can be used alone or in a variety of blends and combinations with Ciba IRGAFOS®, Ciba IRGANOX® and Ciba CHIMASSORB® stabilizers where often a synergistic performance is observed. Drometrizole may react with various heavy metal ions to form salts or complexes. For example, if Drometrizole comes into contact with iron or cobalt ions, colored complexes are formed. Reducing and oxidizing agents used in polymerization and curing processes have no effect on the stability of Drometrizole.

Physical Properties

Drometrizole Physical Properties

Safety

In accordance with good industrial practice, handle with care and avoid unnecessary personal contact. Protect skin. Prevent contamination of the environment. Avoid dust formation and ignition sources.

Chemical Properties

Light yellow powder

Uses

Drometrizole is an intermediate reactant in the synthesis of UV light absorbers for polyester fibers.

Uses

2(2-Hydroxy-5-methylphenyl)benzotriazol is an UV adsorber for use in plastics, cosmetics, dental materials, acrylic materials, dyes, etc.

Uses

An ultraviolet light absorber for stabilizing plastics and other organic materials against discoloration and deterioration.

Application

Intermediate reactant in the synthesis of UV light absorbers for polyester fibers
Reactant for synthesis of:
Benzotriazole UV absorbers with a blocked hydroxy group for us in UV curable paint
Maleimide-bound benzotriazole monomer to use for emulsion polymerization
Used in:
Microstereophotolithography and shape memory alloy for fabrication of miniaturized actuators
PVS and wood / PVC composites as a stabilizer
Acrylonitrile-butadiene-styrene as a UV absorber.

Definition

Drometrizole is a member of triazoles.

Flammability and Explosibility

Not classified

Toxicity evaluation

The mutagenicity study of drometrizole was performed using Salmonella typhimurium strains TA1538 and TA98 with metabolic activation in the Ames’ test. Spot test (10 and 100 mg drometrizole/plate) and top agar method (50 and 100 mg drometrizole/plate) were conducted. The results showed that drometrizole was not mutagenic.Mice and rats were administered 5.0 or 10.0 g/kg of drometrizole in sunflower oil by stomach tube intubation. After body weight and behaviour were monitored for 3 weeks, acute toxicity of drometrizole was evaluated to be low. The oral lethal dose (LD50) of drometrizole in mice was reported to be 6.5 g/kg and > 5.0g/kg. Oral toxicity was evaluated in rats for nail care cosmetics containing 1%, 0.3% and 0.03% of drometrizole. The LD50 of products containing 1% of drometrizole was > 15.0 g/kg. The LD50 of products containing 0.3% and 0.03% drometrizole was > 5.0 g/kg. No acute toxicity was observed in these treatments.

1435-71-8
2440-22-4
Synthesis of Drometrizole from 4-Methyl-2-(2'-nitrophenyl)azophenol

Drometrizole Preparation Products And Raw materials

Global( 503)Suppliers
Supplier Tel Email Country ProdList Advantage
Jiangxi Lotchem Co.,Ltd.
+8615270827708 lancetu@jxlotchem.com CHINA 338 58
Qingdao Truelight functional Material Technology Co., Ltd.
+86-13573844393 songjames@truelightchem.com China 221 58
Hebei Weibang Biotechnology Co., Ltd 		+8615531157085 abby@weibangbio.com China 8810 58
Shaanxi Dideu Medichem Co. Ltd 		+86-29-81148696 +86-15536356810 1022@dideu.com China 3882 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-13131129325 sales1@chuanghaibio.com China 5889 58
Hebei Kingfiner Technology Development Co.Ltd 		+86-15532196582 +86-15373005021 lisa@kingfinertech.com China 3010 58
Shandong Juchuang Chemical Co., LTD 		+undefined15030412209 admin@juchuangchem.com China 387 58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		+8613343047651 admin@zlchemi.com China 3002 58
Hebei Shengyang Water Conservancy Engineering Co., Ltd. 		+8615373025980 clara@hbshengyang.com China 875 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29791 60

Related articles

  • Uses and safety of Drometrizole
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  • Jul 19，2022

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View Lastest Price from Drometrizole manufacturers

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2-(2'-Hydroxy-5'-methyl-phenyl)benzotriazole pictures 2024-12-20 2-(2'-Hydroxy-5'-methyl-phenyl)benzotriazole
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uv absorber P pictures 2024-12-20 uv absorber P
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  • Drometrizole
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  • US $10.00 / kg
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(2'-Hydroxy-5mg-methylphenyl) benzotriazole 2-(2h-benzotriazol-2-yl)-4-methyl-pheno 2-(2h-benzotriazol-2-yl)-p-creso 2-(2-hydroxy-5-methyl-phenyl)-2H-benzotriazole 2-(2-Hydroxy-5-methylphenyl)-2H-benzotriazole 2-Benzotriazolyl-4-methylphenol Lowilite 55 p-Cresol, 2-(2H-benzotriazol-2-yl)- Phenol,2-(2H-benzotriazol-2-yl)-4-methyl- Porex P porexp Tin P tinp Topanex 100BT UltravioletabsorbentUV-P Uvazol P 2-(2’-hydroxy-5-methyl UVSTABILISERS 2-(2-Benzotriazolyl)-4-methylphenol 2-(2-BENZOTRIAZOLYL)-P-CRESOL 2-(2H-BENZOTRIAZOL-2-YL)-4-METHYLPHENOL 2-(2'-HYDROXY-5'-METHYLPHENYL)-BENZOTRIAZOLE 2-(6-HYDROXY-M-TOLYL)-BENZOTRIAZOLE Benazol P DROMETRIZOLE UV Absorber-1 TINUVIN P(R) 2-(2-HYDROXY-5-METHYLPHENYL)BENZOTRIAZOL ThasorbUvp 2-BENZOTRIAZOL-2-YL-4-METHYL-PHENOL UV ABSORBER P 2-(2h-benzotriazol-2-yl)-p-cres 2-(2-BENZOTRIAZOLYL)-P-CRESOL 99+% 2-(5'-Methyl-2'-hydroxyphenyl) benzotriazole 2-(5-Methyl-2-hydroxyphenyl)benzotriazole 2-(2-Hydroxy-5-Methyl-Phenyl)-2H- 2-(2H-Benzotriazole-2-yl)-p-cresol Drometrizole (25 mg) (2-(2H-Benzotriazol-2-yl)-p-cresol) 4-Methyl-2-(2H-benzotriazol-2-yl)phenol Dainsorb T 1 Uvinul 3033P Viosorb 520 2-(2H-Benzo[d][1,2,3]triazol-2-yl)-4-Methylphenol (2'-Hydroxy-5mg-methylphenyl) benzotriazole UV-P Isoprpropanal TinuvinP/2-(2H-Benzotriazol-2-yl)-p-cresol LOTSORB UV P 2-(2-Hydroxy-5-methylphenyl)benzotriazole @1000 μg/mL in Acetonitrile ASTM D6042-96 Internal Std Mix@51.8 μg/mL in Isopropanol Dometrizole 2-(2-Hydroxy-5-methylphenyl)benzotriazole> Drometrizole ISO 9001：2015 REACH UV ABSORBER TRUELICHT UV P UV Absorber UV-P CAS 2440 22 4 UV absorber Sunsorb P JADEADD UV P Light Stabilizer UV-Absorber RIASORB UV-P JADEWIN UVP