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ChemicalBook >> CAS DataBase List >>XPW1

XPW1

CAS No.
2700286-66-2
Chemical Name:
XPW1
Synonyms
XPW1;N-(trans-4-((5'-Chloro-6-((3-fluorobenzyl)amino)-[2,4'-bipyridin]-2'-yl)amino)cyclohexyl)-4-((E)-4-(dimethylamino)but-2-enamido)benzamide;N-(trans-4-((5'-Chloro-6-((3-fluorobenzyl)amino)-[2,4'-bipyridin]-2'-yl)amino)cyclohexyl)-4-((E)-4-(dimethylamino)but-2-enamido)benzamide
CBNumber:
CB613771498
Molecular Formula:
C36H39ClFN7O2
Molecular Weight:
656.19
MDL Number:
MOL File:
2700286-66-2.mol
Last updated:2025-04-18 09:51:18

XPW1 Properties

Boiling point 864.6±65.0 °C(Predicted)
Density 1.31±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
pka 12.98±0.70(Predicted)
form Solid
color Off-white to light yellow

XPW1 Chemical Properties,Uses,Production

Uses

XPW1 is a potent and selective CDK9 inhibitor with excellent activity against clear cell renal cell carcinoma (ccRCC) and low toxicity[1].

References

[1] Kuang Z, et al. The novel CDK9 inhibitor, XPW1, alone and in combination with BRD4 inhibitor JQ1, for the treatment of clear cell renal cell carcinoma. Br J Cancer. 2023 Oct 26. DOI:10.1038/s41416-023-02464-y

XPW1 Preparation Products And Raw materials

Raw materials

Preparation Products

XPW1 Suppliers

Global( 11)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32275 58
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 71826 60
Shanghai Chaolan Chemical Technology Center 021-QQ：65489617 15618227136 Sales@ATKchemical.com China 9346 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 62321 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
Hubei wei shi reagent group ltd., company 027-59101766 13125137661 2853877621@qq.com China 8000 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 20026 58
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd 025-58851090 17714375163 2881759498@qq.com China 13012 58
Sangon Biotech (Shanghai) Co.,Ltd. 400-821-026 Sales@sangon.com China 55710 58

View Lastest Price from XPW1 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
XPW1 pictures 2024-11-19 XPW1
2700286-66-2
 US $105.00-416.00 / mg 98.08% 10g TargetMol Chemicals Inc.
  • XPW1 pictures
  • XPW1
    2700286-66-2
  • US $105.00-416.00 / mg
  • 98.08%
  • TargetMol Chemicals Inc.
XPW1 N-(trans-4-((5'-Chloro-6-((3-fluorobenzyl)amino)-[2,4'-bipyridin]-2'-yl)amino)cyclohexyl)-4-((E)-4-(dimethylamino)but-2-enamido)benzamide N-(trans-4-((5'-Chloro-6-((3-fluorobenzyl)amino)-[2,4'-bipyridin]-2'-yl)amino)cyclohexyl)-4-((E)-4-(dimethylamino)but-2-enamido)benzamide 2700286-66-2