Eliapixant
- CAS No.
- 1948229-21-7
- Chemical Name:
- Eliapixant
- Synonyms
- BAY 1817080;Eliapixant;Eliapixant（BAY 1817080）;Eliapixant, 10 mM in DMSO;Inhibitor,chronic,Eliapixant,cough,refractory,BAY-1817080,P2X Receptor,BAY1817080,P2X3,inhibit,P2XRs;3-(5-Methylthiazol-2-yl)-5-(((R)-tetrahydrofuran-3-yl)oxy)-N-((R)-1-(2-(trifluoromethyl)pyrimidin-5-yl)ethyl)benzamide;Benzamide, 3-(5-methyl-2-thiazolyl)-5-[[(3R)-tetrahydro-3-furanyl]oxy]-N-[(1R)-1-[2-(trifluoromethyl)-5-pyrimidinyl]ethyl]-
- CBNumber:
- CB58240555
- Molecular Formula:
- C22H21F3N4O3S
- Molecular Weight:
- 478.49
- MDL Number:
- MFCD34470055
- MOL File:
- 1948229-21-7.mol
| Density | 1.360±0.06 g/cm3(Predicted) |
|---|---|
| pka | 13.02±0.46(Predicted) |
| form | Solid |
| color | White to off-white |
| FDA UNII | 9GH7E6347B |
Eliapixant Chemical Properties,Uses,Production
Uses
Eliapixant (BAY 1817080) is a potent and selective antagonist of P2X3 receptor, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough[1][2].
in vivo
Eliapixant can be used for the research of coughs and diabetes complications[1].
IC 50
P2X3 Receptor
References
[1] Spinaci A, et, al. P2X3 Receptor Ligands: Structural Features and Potential Therapeutic Applications. Front Pharmacol. 2021 Apr 13;12:653561. DOI:10.3389/fphar.2021.653561
[2] Morice A, et, al. Eliapixant (BAY 1817080), a P2X3 receptor antagonist, in refractory chronic cough: a randomised, placebo-controlled, crossover phase 2a study. Eur Respir J. 2021 May 13;2004240. DOI:10.1183/13993003.04240-2020
Eliapixant Preparation Products And Raw materials
Raw materials
Preparation Products
Eliapixant Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 32292 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3135 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38669 | 58 | |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3475 | 58 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4621 | 55 | |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71826 | 60 |
View Lastest Price from Eliapixant manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-12 | Eliapixant
1948229-21-7
|
US $98.00-328.00 / mg | 98.65% | 10g | TargetMol Chemicals Inc. |
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- Eliapixant
1948229-21-7
- US $98.00-328.00 / mg
- 98.65%
- TargetMol Chemicals Inc.