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ChemicalBook >> CAS DataBase List >>NSC135784

NSC135784

CAS No.
74578-01-1
Chemical Name:
NSC135784
Synonyms
Thaspine HCl;Thaspine acetate;Thaspine HCl, NSC 135784
CBNumber:
CB55493266
Molecular Formula:
C22H23NO8
Molecular Weight:
429.43
MDL Number:
MOL File:
74578-01-1.mol
Last updated:2024-10-28 23:16:16

NSC135784 Chemical Properties,Uses,Production

Description

Thaspine, also known as NSC 135784, is a natural compound and a potent topoisomerase IB inhibitor. Taspine downregulates VEGF expression and inhibits proliferation of vascular endothelial cells through PI3 kinase and MAP kinase signaling pathways. Taspine isolated from Radix et Rhizoma Leonticis inhibits proliferation and migration of endothelial cells as well as chicken chorioallantoic membrane neovascularisation. Croton lechleri sap and isolated alkaloid taspine exhibit inhibition against human melanoma SK23 and colon cancer HT29 cell lines.

NSC135784 Preparation Products And Raw materials

Raw materials

Preparation Products

NSC135784 Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
TargetMol Chemicals Inc.
+8613564774135 zijue.cai@tsbiochem.com United States 19884 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19703 58

View Lastest Price from NSC135784 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Thaspine acetate pictures 2024-10-28 Thaspine acetate
74578-01-1
US $1820.00-3100.00 / mg 10g TargetMol Chemicals Inc.
Thaspine HCl Thaspine HCl, NSC 135784 Thaspine acetate 74578-01-1