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ChemicalBook >> CAS DataBase List >>Triethyl acetyl citrate

Triethyl acetyl citrate

CAS No.
77-89-4
Chemical Name:
Triethyl acetyl citrate
Synonyms
ACETYL TRIETHYL CITRATE;ATEC;O-AcetyL;triethyl 2-acetoxypropane-1,2,3-tricarboxylate;Uniplex 82;Triethyl O;citroflexa2;Citroflex A 2;Trithylcitratc;ethyl acetylcitrate
CBNumber:
CB5483819
Molecular Formula:
C14H22O8
Molecular Weight:
318.32
MDL Number:
MFCD00049378
MOL File:
77-89-4.mol
MSDS File:
SDS
Last updated:2024-12-18 14:08:57

Triethyl acetyl citrate Properties

Melting point -42°C
Boiling point 228-229 °C/100 mmHg (lit.)
Density 1.136 g/mL at 25 °C (lit.)
Pour Point -42
refractive index n20/D 1.439(lit.)
Flash point >230 °F
storage temp. Inert atmosphere,Room Temperature
solubility Soluble 1 in 140 of water; miscible with acetone, ethanol, and propan-2-ol.
form Liquid
color Colourless
Odor odorless
Viscosity 53.7cp (25C)
BRN 1804947
LogP 2.170 (est)
CAS DataBase Reference 77-89-4(CAS DataBase Reference)
Indirect Additives used in Food Contact Substances ACETYL TRIETHYL CITRATE
FDA 21 CFR 175.105; 175.300; 175.320; 178.3910; 181.27
EWG's Food Scores 2
FDA UNII 5WBR36T90E
NIST Chemistry Reference 1,2,3-Propanetricarboxylic acid, 2-acetoxy-, triethyl ester(77-89-4)
EPA Substance Registry System 1,2,3-Propanetricarboxylic acid, 2-(acetyloxy)-, triethyl ester (77-89-4)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
Safety Statements  23-24/25
WGK Germany  1
RTECS  GE8225000
TSCA  TSCA listed
HS Code  2918150000
NFPA 704
1
0 0

Triethyl acetyl citrate price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 388351 Triethyl 2-acetylcitrate 99% 77-89-4 500ml $61.8 2024-03-01 Buy
Sigma-Aldrich 1009923 Acetyltriethyl citrate United States Pharmacopeia (USP) Reference Standard 77-89-4 500mg $450 2022-05-15 Buy
TCI Chemical A0086 Triethyl O-Acetylcitrate >97.0%(GC) 77-89-4 25g $33 2024-03-01 Buy
TCI Chemical A0086 Triethyl O-Acetylcitrate >97.0%(GC) 77-89-4 500g $68 2024-03-01 Buy
scipoly P-108 Acetyl triethyl citrate 77-89-4 100g $14 2024-07-03 Buy
Product number Packaging Price Buy
388351 500ml $61.8 Buy
1009923 500mg $450 Buy
A0086 25g $33 Buy
A0086 500g $68 Buy
P-108 100g $14 Buy

Triethyl acetyl citrate Chemical Properties,Uses,Production

Chemical Properties

Acetyltriethyl citrate occurs as a clear, odorless, practically colorless oily liquid.

Uses

Triethyl O-Acetylcitrate is used in the preparation of poly(lactic) acid biodegradable and flexible films, acting as a plasticizer. Also used in the synthesis of control-release capsules containing polymeric coatings.

Uses

ATEC is produced by the reaction of citric acid triethyl ester with acetic acid anhydride. It is used as a solvent plasticizer for cellulose nitrate and cellulose acetate.

Production Methods

Acetyltriethyl citrate is prepared by the esterification of citric acid with ethanol followed by acylation with acetic anhydride.

Definition

Aqueous-based pharmaceutical coat- ings.

General Description

Certified pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Triethyl 2-acetylcitrate is widely used in hydrophilic adhesives for medications and in biodegradable composition for papermaking and nonwoven production.

Pharmaceutical Applications

Acetyltriethyl citrate is used to plasticize polymers in formulated pharmaceutical coatings. The coating applications include capsules, tablets, beads and granules for taste masking, immediate release, sustained-release and enteric formulations. It is also used in diffusion-controlled release drug delivery systems.

Safety

Acetyltriethyl citrate is used in oral pharmaceutical formulations and is generally regarded as a nontoxic and nonirritating material. However, ingestion of large quantities may be harmful.
LD50 (cat, oral): 8.5 g/kg
LD50 (mouse, IP): 1.15 g/kg
LD50 (rat, oral): 7 g/kg

storage

Acetyltriethyl citrate should be stored in dry, closed containers at temperatures not exceeding 388℃. When stored in accordance with these conditions, acetyltriethyl citrate is a stable product.

Incompatibilities

Acetyltriethyl citrate is incompatible with strong alkalis and oxidizing materials.

Regulatory Status

Approved in the USA for direct food contact in food films.

77-93-0
108-24-7
77-89-4
Synthesis of Triethyl acetyl citrate from Triethyl citrate and Acetic anhydride

Triethyl acetyl citrate Preparation Products And Raw materials

Global( 263)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd 		+86 13288715578 +8613288715578 sales@hbmojin.com China 12835 58
Hebei Yanxi Chemical Co., Ltd. 		+8617531190177 peter@yan-xi.com China 5857 58
Hebei Weibang Biotechnology Co., Ltd 		+8617732866630 bess@weibangbio.com China 18151 58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		+8613343047651 admin@zlchemi.com China 3002 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29880 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28172 58
Xi'an Kono chem co., Ltd., 		029-86107037 13289246953 info@konochemical.com China 1169 58
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22963 58
Shanghai Longyu Biotechnology Co., Ltd. 		+8619521488211 info@longyupharma.com China 2541 58

View Lastest Price from Triethyl acetyl citrate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Acetyl Triethyl Citrate pictures 2024-12-20 Acetyl Triethyl Citrate
77-89-4
 US $200.00-95.00 / kg 1kg 99% 20ton Hebei Zhuanglai Chemical Trading Co.,Ltd
Triethyl acetyl citrate pictures 2024-12-20 Triethyl acetyl citrate
77-89-4
 US $100.00 / kg 1kg 98 4000 Hebei Zhuanglai Chemical Trading Co.,Ltd
Triethyl acetyl citrate pictures 2024-10-30 Triethyl acetyl citrate
77-89-4
 US $0.00-0.00 / KG 1KG 99% 500000kg Hebei Weibang Biotechnology Co., Ltd
1,2,3-Propanetricarboxylic acid, 2-(acetyloxy)-, triethyl ester 1,2,3-Propanetricarboxylicacid,2-(acetyloxy)-,triethylester 2,3-propanetricarboxylicacid,2-(acetyloxy)-triethylester Citric acid, acetyl triethyl ester Citric acid, triethyl ester, acetate citricacid,acetyltriethylester citricacid,triethylester,acetate Citroflex A 2 citroflexa2 o-Acetyl-triethylcitrate 2-(Acetyloxy)-1,2,3-propanetricarboxylic acid triethyl ester O-ACETYLCITRIC ACID TRIETHYL ESTER triethyl acetyl citrate TRIETHYL O-ACETYLCITRATE Tricarballylic acid, beta-acetoxytributyl ester tricarballylicacid,beta-acetoxytributylester Triethyl 2-(acetyloxy)-1,2,3-propanetricarboxylate Triethyl 2-acetoxy-1,2,3-propanetricarboxylate Triethyl citrate acetate triethylcitrate,acetate Triethylester kyseliny acetylcitronove triethylesterkyselinyacetylcitronove Trithylcitratc Uniplex 82 Triethyl-O-acetylcitrat Triethyl 2-acetylcitrate ethyl acetylcitrate triethyl acetocitrate 1,2,3-Triethyl 2-acetyloxypropane-1,2,3-tricarboxylate 2-Acetoxy-1,2,3-propanetricarboxylic acid triethyl ester 2-Acetoxypropane-1,2,3-tricarboxylic acid triethyl ester Acetyl triethyl citrate 10g [77-89-4] Triethyl 2-acetylcitrate,Acetyl triethyl citrate Acetyltriethyl Citrate (500 mg) Triethyl 2-acetylcitr 1,2,3-Propanetricarboxylicacid, 2-(acetyloxy)-, 1,2,3-triethyl ester Triethyl 2-acetylcitrate 99% Triethyl O-Acetylcitrate > Triethyl O Triethyl acetyl citrate ISO 9001：2015 REACH ATEC ACETYL TRIETHYL CITRATE triethyl 2-acetoxypropane-1,2,3-tricarboxylate O-AcetyL Methyl Iodide (lodomethane) Acetyltriethyl Citrate (100 mg) 77-89-4 77-88-4 CH3COOCCOOCH2CH3CH2COOCH2CH32 Hydroxycarboxylic Acid Esters (Plasticizer) Plasticizer Esters Organic Building Blocks Building Blocks Carbonyl Compounds C12 to C63 Hydroxycarboxylic Acid Esters (Plasticizer) Functional Materials