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ChemicalBook >> CAS DataBase List >>5,6-dimethyl-4-(2-methylphenoxy)thieno[2,3-d]pyrimidine

5,6-dimethyl-4-(2-methylphenoxy)thieno[2,3-d]pyrimidine

CAS No.
302952-43-8
Chemical Name:
5,6-dimethyl-4-(2-methylphenoxy)thieno[2,3-d]pyrimidine
Synonyms
MRGPRX1 agonist 2;5,6-dimethyl-4-(2-methylphenoxy)thieno[2,3-d]pyrimidine;Thieno[2,3-d]pyrimidine, 5,6-dimethyl-4-(2-methylphenoxy)-
CBNumber:
CB54591150
Molecular Formula:
C15H14N2OS
Molecular Weight:
270.35
MDL Number:
MOL File:
302952-43-8.mol
Last updated:2025-04-28 21:36:36

5,6-dimethyl-4-(2-methylphenoxy)thieno[2,3-d]pyrimidine Properties

Boiling point 413.3±40.0 °C(Predicted)
Density 1.235±0.06 g/cm3(Predicted)
pka 2.36±0.40(Predicted)

5,6-dimethyl-4-(2-methylphenoxy)thieno[2,3-d]pyrimidine Chemical Properties,Uses,Production

Uses

MRGPRX1 agonist 2 (compound 1a) is a potent Mas-related G protein-coupled receptor X1 (MRGPRX1) positive allosteric modulator with an EC50 value of 0.48 μM. MRGPRX1 agonist 2 can be used for researching neuropathic pain[1].

References

[1] Berhane I, et al. Thieno[2,3-d]pyrimidine-Based Positive Allosteric Modulators of Human Mas-Related G Protein-Coupled Receptor X1 (MRGPRX1). J Med Chem. 2022;65(4):3218-3228. DOI:10.1021/acs.jmedchem.1c01709

5,6-dimethyl-4-(2-methylphenoxy)thieno[2,3-d]pyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

5,6-dimethyl-4-(2-methylphenoxy)thieno[2,3-d]pyrimidine Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+17819995354 marketing@targetmol.com United States 19904 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 21356 58

View Lastest Price from 5,6-dimethyl-4-(2-methylphenoxy)thieno[2,3-d]pyrimidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
MRGPRX1 agonist 2 pictures 2025-04-28 MRGPRX1 agonist 2
302952-43-8
US $2500.00-1520.00 / mg 10g TargetMol Chemicals Inc.
5,6-dimethyl-4-(2-methylphenoxy)thieno[2,3-d]pyrimidine MRGPRX1 agonist 2 Thieno[2,3-d]pyrimidine, 5,6-dimethyl-4-(2-methylphenoxy)- 302952-43-8