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ChemicalBook >> CAS DataBase List >>Pan-RAS-IN-1

Pan-RAS-IN-1

CAS No.
1835283-94-7
Chemical Name:
Pan-RAS-IN-1
Synonyms
Ras-IN-3144;Pan-RAS-IN-1;Pan-RAS inhibitor 1;pan-Ras inhibitor 3144;Ras-IN-3144，Pan-RAS-IN-1;Pan-RAS-IN-1, 10 mM in DMSO;pan-Ras inhibitor 3144 (Compound 3144);PanRASIN1,inhibit,Ras,Pan RAS IN 1,Inhibitor;4-Piperidinecarboxamide, 4-amino-N-[3-[5-[[4-[(2,6-dichlorophenyl)methyl]-1-piperazinyl]methyl]-3-[4-(trifluoromethoxy)phenyl]-1H-indol-1-yl]propyl]-
CBNumber:
CB53171698
Molecular Formula:
C36H41Cl2F3N6O2
Molecular Weight:
717.65
MDL Number:
MFCD31382126
MOL File:
1835283-94-7.mol
Last updated:2025-04-30 20:12:30

Pan-RAS-IN-1 Properties

Boiling point 809.7±65.0 °C(Predicted)
Density 1.38±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : ≥ 50 mg/mL (69.67 mM)
form Solid
pka 17.09±0.20(Predicted)
color White to yellow

Pan-RAS-IN-1 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-6466 Pan-RAS-IN-1 99.87% 1835283-94-7 1mg $180 2021-12-16 Buy
ChemScene CS-6466 Pan-RAS-IN-1 99.87% 1835283-94-7 5mg $420 2021-12-16 Buy
ChemScene CS-6466 Pan-RAS-IN-1 99.87% 1835283-94-7 10mg $720 2021-12-16 Buy
ChemScene CS-6466 Pan-RAS-IN-1 99.87% 1835283-94-7 25mg $1440 2021-12-16 Buy
ChemScene CS-6466 Pan-RAS-IN-1 99.87% 1835283-94-7 50mg $2340 2021-12-16 Buy
Product number Packaging Price Buy
CS-6466 1mg $180 Buy
CS-6466 5mg $420 Buy
CS-6466 10mg $720 Buy
CS-6466 25mg $1440 Buy
CS-6466 50mg $2340 Buy

Pan-RAS-IN-1 Chemical Properties,Uses,Production

Uses

Pan-RAS-IN-1 is a pan-Ras inhibitor that disrupts the interaction of Ras proteins and their effectors.

in vivo

Pan-RAS-IN-1 administration results in inhibition of tumor growth over 15 days of treatment. Pan-RAS-IN-1-treated mice exhibits decreased tumor pERK levels compared with vehicle treated mice. A modest increase in cleaved caspase-3 is also observed, showing that in this model, pan-RAS-IN-1 has the capacity to induce caspase activation[1].

References

[1] Welsch ME, et al. Multivalent Small-Molecule Pan-RAS Inhibitors. Cell. 2017 Feb 23;168(5):878-889.e29. DOI:10.1016/j.cell.2017.02.006

Pan-RAS-IN-1 Preparation Products And Raw materials

Raw materials

Preparation Products

Pan-RAS-IN-1 Suppliers

Global( 32)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32275 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185 sales-cpd@caerulumpharma.com China 3467 58
Bide Pharmatech Ltd. 400-164-7117 13681763483 product02@bidepharm.com China 42446 60
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 71826 60
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9729 58
BOC Sciences -- info@bocsci.com USA 0 65
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
Shanghai hongqu biomedical technology co. LTD 88888888888 hongquchem@qq.com China 5132 58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 15317229551 15151849396@163.com China 997 58

View Lastest Price from Pan-RAS-IN-1 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Pan-RAS-IN-1 pictures 2025-04-30 Pan-RAS-IN-1
1835283-94-7
 US $73.00-147.00 / mg 98.57% 10g TargetMol Chemicals Inc.
  • Pan-RAS-IN-1 pictures
  • Pan-RAS-IN-1
    1835283-94-7
  • US $73.00-147.00 / mg
  • 98.57%
  • TargetMol Chemicals Inc.

Pan-RAS-IN-1 Spectrum

Pan-RAS-IN-1 pan-Ras inhibitor 3144 Pan-RAS inhibitor 1 4-Piperidinecarboxamide, 4-amino-N-[3-[5-[[4-[(2,6-dichlorophenyl)methyl]-1-piperazinyl]methyl]-3-[4-(trifluoromethoxy)phenyl]-1H-indol-1-yl]propyl]- pan-Ras inhibitor 3144 (Compound 3144) Ras-IN-3144，Pan-RAS-IN-1 Ras-IN-3144 PanRASIN1,inhibit,Ras,Pan RAS IN 1,Inhibitor Pan-RAS-IN-1, 10 mM in DMSO 1835283-94-7 C36H41Cl2F3N6O2