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ChemicalBook >> CAS DataBase List >>Ginsenoside Re

Ginsenoside Re

CAS No.
52286-59-6
Chemical Name:
Ginsenoside Re
Synonyms
DCR-020;Panaxoside;NSC 308877;ginsenosideb2;GINSENOSIDE RE;Sanchinoside Re;98%byHPLC/CH90650;Re Ginsenoside Re;Ginsenoside Re-RM;Ginsenoside Re (P)
CBNumber:
CB5210824
Molecular Formula:
C48H82O18
Molecular Weight:
947.17
MDL Number:
MFCD00133369
MOL File:
52286-59-6.mol
Last updated:2025-04-17 18:22:24

Ginsenoside Re Properties

Melting point 201～203℃
Boiling point 1011.8±65.0 °C(Predicted)
Density 1.38±0.1 g/cm3(Predicted)
storage temp. Inert atmosphere,2-8°C
solubility DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly)
pka 12.85±0.70(Predicted)
form Solid
color White to Off-White
InChIKey PWAOOJDMFUQOKB-WCZZMFLVSA-N
LogP 4.750 (est)
CAS DataBase Reference 52286-59-6(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 46F3R0BL3I
UNSPSC Code 85151701
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P501
Hazard Codes  Xn
Risk Statements  20/21/22
Safety Statements  26-36
WGK Germany  3
RTECS  LY9536700
HS Code  29389090
NFPA 704
0
2 0

Ginsenoside Re price More Price(45)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHL89212 Ginsenoside Re phyproof? Reference Substance 52286-59-6 10mg $240 2024-03-01 Buy
Sigma-Aldrich 77960 Ginsenoside Re analytical standard 52286-59-6 10mg $388 2024-03-01 Buy
Sigma-Aldrich 03000590 Ginsenoside Re primary pharmaceutical reference standard 52286-59-6 10mg $270.8 2024-03-01 Buy
TCI Chemical G0551 Ginsenoside Re 52286-59-6 50MG $169 2024-03-01 Buy
TCI Chemical G0551 Ginsenoside Re 52286-59-6 250MG $522 2024-03-01 Buy
Product number Packaging Price Buy
PHL89212 10mg $240 Buy
77960 10mg $388 Buy
03000590 10mg $270.8 Buy
G0551 50MG $169 Buy
G0551 250MG $522 Buy

Ginsenoside Re Chemical Properties,Uses,Production

Chemical Properties

White solid

Uses

Ginsenoside Re is an extract from ginger, responsible for some of the pharmacological functions. It displays cardiac contractility, anti-ischemic and anti-arrythmic activities.

Definition

ChEBI: Ginsenoside Re is a ginsenoside found in Panax ginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranoside and beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position. It has a role as a plant metabolite, an antioxidant, a neuroprotective agent, an anti-inflammatory agent, an antineoplastic agent and a nephroprotective agent. It is a 12beta-hydroxy steroid, a 3beta-hydroxy steroid, a beta-D-glucoside, a ginsenoside, a tetracyclic triterpenoid, a disaccharide derivative and a 3beta-hydroxy-4,4-dimethylsteroid. It derives from a hydride of a dammarane.

in vivo

Ginsenoside Re reduces insulin resistance in 3T3-L1 adipocytes and high-fat diet (HFD) rats through inhibition of JNK and NF-κB activation[2]. Intraperitoneal injection of lipopolysaccharide (LPS) at a dose of 20 mg/kg is lethal to mice, and 70% to 80% of the mice die within 60 h. However, pretreatment of the mice with Rg1 or Ginsenoside Re increases their survival rates in a dose-dependent manner. With the doses of Rg1 or Ginsenoside Re increase from 2.5 to 5 mg/kg, the survival rate is elevated from 60% to 90% (Rg1) or from 30% to 40% (Ginsenoside Re). All the mice administered Rg1 at a minimal dose of 10 mg/kg are protected from death compared to 80% survival of mice treated with an equal dose of Ginsenoside Re. To protect all the mice, 20 mg/kg Ginsenoside Re is needed. To investigate the anti-inflammatory potential of Rg1 and Ginsenoside Re, 1 mg/kg Rg1 or Ginsenoside Re is injected into rats and then challenged the animals with LPS. The injection procedure itself causes a transient stress-induced increase in body temperature of ~1.2°C in each group. Thereafter, LPS-challenged rats without pretreatment develope a robust biphasic fever, with the first peak reaching ~1.5°C at 2 h and the second peak reaching 1.8°C at 4 h. In contrast, the temperature changes for the Rg1-, Ginsenoside Re-, and TAK-242-treated groups are only 0.9, 1.2, and 0.8°C at 2 h and 1.3, 1.4, and 1.0°C at 4 h, respectively. Pretreatment with Rg1, Ginsenoside Re, or TAK-242 significantly attenuates LPS-induced alterations in body temperature[3].

target

AMPK | TLR | p38MAPK | HO-1 | TNF-α | Potassium Channel | NO | Calcium Channel | ERK | Akt | mTOR | CD4 | Calcium Channel | c-Src | NOS

IC 50

Aβ1-40; Aβ1-42; NF-κB; JNK

Ginsenoside Re Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 314)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
+8618791163155 18791163155@163.com China 3558 58
Apeloa production Co.,Limited 		+8619933239880 admin@apcl.com.cn China 861 58
Shanghai Zheyan Biotech Co., Ltd. 		18017610038 zheyansh@163.com CHINA 3619 58
Chengdu Biopurify Phytochemicals Ltd. 		+86-28-82633860; +8618080483897 sales@biopurify.com China 3772 58
Nanjing Dolon Biotechnology Co.,Ltd. 		18905173768 sales@dolonchem.com CHINA 2972 58
Shaanxi Pioneer Biotech Co., Ltd . 		+8613259417953 sales@pioneerbiotech.com China 1287 58
NanJing Spring & Autumn Biological Engineering CO., LTD. 		+8613815430202 sale02@cqherb.com CHINA 376 58
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22963 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19552 58
Shanghai Standard Technology Co., Ltd. 		18502101150 ft-sales@nature-standard.com CHINA 1923 58

View Lastest Price from Ginsenoside Re manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ginsenoside Re pictures 2025-02-13 Ginsenoside Re
52286-59-6
 US $1.00 / g 1g 98% 1000 Apeloa production Co.,Limited
Ginsenoside Re pictures 2024-11-19 Ginsenoside Re
52286-59-6
 US $43.00-98.00 / mg 99.78% 10g TargetMol Chemicals Inc.
Ginsenoside Re pictures 2023-02-24 Ginsenoside Re
52286-59-6
 US $0.00 / mg 5mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
  • Ginsenoside Re pictures
  • Ginsenoside Re
    52286-59-6
  • US $43.00-98.00 / mg
  • 99.78%
  • TargetMol Chemicals Inc.
  • Ginsenoside Re pictures
  • Ginsenoside Re
    52286-59-6
  • US $0.00 / mg
  • ≥98%(HPLC)
  • Shanghai Standard Technology Co., Ltd.

Ginsenoside Re Spectrum

chikusetsusaponinivc b-D-Glucopyranoside, (3b,6a,12b)-20-(b-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl2-O-(6-deoxy-a-L-mannopyranosyl)- (3β,6α,12β)-20-(β-D-Glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside ginsenosideb2 GINSENOSIDE GINSENOSIDE-RE GINSENOSIDE RE 2-O-(6-deoxy-alpha-L-mannopyranosyl)-(3beta,6alpha,12beta)-20-(beta-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl-beta-D-glucopyranoside Ginsenoside Re std. 98%byHPLC/CH90650 Panaxoside GINSENOSIDE RE WITH HPLC GINSENOSIDE-RE (GINSENOSIDE B2) NSC 308877 Sanchinoside Re Panaxoside RE, Ginsenoside B2, Chikusetsusaponin IVc glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl2-O-(6-deoxy-α-L-mannopyranosyl)- β-D-Glucopyranoside,(3β,6α,12β)-20-(β-D- [20-(β-D-Glucopyranosyloxy)-3β,12β-dihydroxy-5α-dammar-24-en-6α-yl]2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside [20-(β-D-Glucopyranosyloxy)-3β,12β-dihydroxydammar-24-en-6α-yl]2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside 20-(β-D-Glucopyranosyloxy)-3β,12β-dihydroxy-5α-dammar-24-en-6α-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside ginsenoside-Re standard Ginsenoside Re ,97% DCR-020 DCR-020;PANAXOSIDE RE;GINSENOSIDE B2;CHIKUSETSUSAPONIN IVC Ginsenoside Re 52286-59-6 β-D-Glucopyranoside, (3β,6α,12β)-20-(β-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-α-L-mannopyranosyl)- (2S,3R,4R,5R,6S)-2-(((1R,2S,3R,4R,6R)-6-(((3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-17-((S)-1-hydroxy-5-methyl-1-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hex-4-en-1-yl)-4,4,8,10,14-pentamethylhexadecahydro-1H-cyclopenta[a]phenanthren-6-yl)oxy)-2,3-dihydroxy-4-(hydroxymethyl)cyclohexyl)oxy)-6-methyltetrahydro-2H-pyran-3,4,5-triol (2S,3R,4R,5R,6S)-2-(((2R,3R,4S,5S,6R)-2-(((3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-((S)-6-methyl-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hept-5-en-2-yl)hexadecahydro-1H-cycl (3beta,6alpha,12beta)-20-(beta-D-Glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-6-Deoxy-alpha-L-mannopyranosyl-beta-D-glucopyranoside (2S,3R,4R,5R,6S)-2-[(2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-6-methyloxane-3,4,5-triol 4-?Dihydroxyphenyl)?ethanone Ginsenoside Re (P) (2S,3R,4R,5R,6S)-2-(((2R,3R,4S,5S,6R)-2-(((3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-Dihydroxy-4,4,8,10,14-pentamethyl-17-((S)-6-methyl-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hept-5-en-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-6-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-methyltetrahydro-2H-pyran-3,4,5-triol Re Ginsenoside Re Ginsenoside Re(AS) Ginsenoside Re-RM β-?D-?Glucopyranoside, (3β,?6α,?12β)?-?20-?(β-?D-?glucopyranosyloxy)?-?3,?12-?dihydroxydammar-?24-?en-?6-?yl 2-?O-?(6-?deoxy-?α-?L-?mannopyranosyl)?- 52286-59-6 197-70-5 C48H82O18 Inhibitors Ginsenoside series chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract The group of Ginsenosides Saponins