1,3-dipropyl-8-(3-noradamantyl)xanthine
- CAS No.
- 136199-02-5
- Chemical Name:
- 1,3-dipropyl-8-(3-noradamantyl)xanthine
- Synonyms
- MK-7418;KW-3902;HMR-4902;Rolofylline;KW-3902 >=98% (HPLC);Rolofylline, 10 mM in DMSO;KW-3902|||MK-7418|||KF-15372;1,3-dipropyl-8-(3-noradamantyl)xanthine;8-(Hexahydro-2,5-methano-pentalen-3a-yl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione;8-(Hexahydro-2,5-methanopentalen-3a(1H)-yl)-3,7-dihydro-1,3-dipropyl-1H-purine-2,6-dione
- CBNumber:
- CB51337919
- Molecular Formula:
- C20H28N4O2
- Molecular Weight:
- 356.46
- MDL Number:
- MFCD00899862
- MOL File:
- 136199-02-5.mol
- MSDS File:
- SDS
| Boiling point | 578.0±42.0 °C(Predicted) |
|---|---|
| Density | 1.262±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: soluble20mg/mL |
| form | solid |
| pka | 9.23±0.70(Predicted) |
| color | White to off-white |
| FDA UNII | 7805S5HIHX |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
1,3-dipropyl-8-(3-noradamantyl)xanthine price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | K3769 | KW-3902 ≥98% (HPLC) | 136199-02-5 | 5mg | $165 | 2024-03-01 | Buy |
| Sigma-Aldrich | K3769 | KW-3902 ≥98% (HPLC) | 136199-02-5 | 25mg | $660 | 2024-03-01 | Buy |
| Cayman Chemical | 11940 | KW 3902 ≥98% | 136199-02-5 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 11940 | KW 3902 ≥98% | 136199-02-5 | 5mg | $139 | 2024-03-01 | Buy |
| Cayman Chemical | 11940 | KW 3902 ≥98% | 136199-02-5 | 10mg | $199 | 2024-03-01 | Buy |
1,3-dipropyl-8-(3-noradamantyl)xanthine Chemical Properties,Uses,Production
Description
KW 3902 is an antagonist of the adenosine A1 receptor (Ki = 0.19 nM). It displays 890-fold selectivity for A1 receptors over A2A receptors and has no activity at A3 receptors. KW 3902 less potently inhibits human organic anion transporter 1 (OAT1; Ki = 7.82 μM). KW 3902 exhibits renal protective effects during hypoxemia in rabbits.
Uses
KW 3902 is an adenosine A1-receptor antagonist, which has recently been shown to alleviate axonopathy caused by human Tau ΔK280. KW 3902 can be considered for the development of a treatment towards hypometabolism and neuronal dysfunction associated with Tau-induced neurodegenerative diseases.
Definition
ChEBI: Rolofylline is an oxopurine.
storage
Store at +4°C
1,3-dipropyl-8-(3-noradamantyl)xanthine Preparation Products And Raw materials
Raw materials
Preparation Products
1,3-dipropyl-8-(3-noradamantyl)xanthine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 32281 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30230 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8447 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
| Shanghai Rechem science Co., Ltd. | 21-31433387 15618786686 | sales@rechemscience.com | China | 2984 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44813 | 58 |
View Lastest Price from 1,3-dipropyl-8-(3-noradamantyl)xanthine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-12 | Rolofylline
136199-02-5
|
US $39.00-118.00 / mg | 99.53% | 10g | TargetMol Chemicals Inc. |
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- Rolofylline
136199-02-5
- US $39.00-118.00 / mg
- 99.53%
- TargetMol Chemicals Inc.