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ChemicalBook >> CAS DataBase List >>4H-Dibenzo[de,g]quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride, hydrate (1:1:), (6aR)-

4H-Dibenzo[de,g]quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride, hydrate (1:1:), (6aR)-

CAS No.
58117-94-5
Chemical Name:
4H-Dibenzo[de,g]quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride, hydrate (1:1:), (6aR)-
Synonyms
4H-Dibenzo[de,g]quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride, hydrate (1:1:), (6aR)-
CBNumber:
CB512121745
Molecular Formula:
C17H20ClNO3
Molecular Weight:
321.8
MDL Number:
MOL File:
58117-94-5.mol
Last updated:2024-10-28 23:16:16

4H-Dibenzo[de,g]quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride, hydrate (1:1:), (6aR)- Properties

solubility DMF: 20 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 15 mg/ml; Ethanol: 1 mg/ml
form A crystalline solid

SAFETY

Risk and Safety Statements

4H-Dibenzo[de,g]quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride, hydrate (1:1:), (6aR)- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 16094 (?)-Apomorphine (hydrochloride hydrate) ≥95% 58117-94-5 10 mg $32 2024-03-01 Buy
Cayman Chemical 16094 (?)-Apomorphine (hydrochloride hydrate) ≥95% 58117-94-5 50 mg $70 2024-03-01 Buy
Cayman Chemical 16094 (?)-Apomorphine (hydrochloride hydrate) ≥95% 58117-94-5 100 mg $122 2024-03-01 Buy
Product number Packaging Price Buy
16094 10 mg $32 Buy
16094 50 mg $70 Buy
16094 100 mg $122 Buy

4H-Dibenzo[de,g]quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride, hydrate (1:1:), (6aR)- Chemical Properties,Uses,Production

Description

(?)-Apomorphine is a non-selective dopamine receptor agonist that exhibits pKi values of 6.43, 7.08, 7.59, 8.36, and 7.83 for human recombinant D1, D2L, D3, D4, and D5 receptors, respectively.1,2 It produces biphasic effects on locomotor activity and displays anti-parkinsonian and neuroprotective actions.1,3,4

References

1. Millan, M.J., Maiofiss, L., Cussac, D., et al. Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. I. A multivariate analysis of the binding profiles of 14 drugs at 21 native and cloned human receptor subtypes J. Pharmacol. Exp. Ther. 303(2),791-804(2002).
2. Seeman, P., Grigoriadis, D.E., and Niznik, H.B. Selectivity of agonists and antagonists at D2 dopamine receptors compared to D1 and S2 receptors Drug Dev. Res. 9,63-69(1986).
3. Newman-Tancredi, A., Cussac, D., Audinot, V., et al. Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. II. Agonist and antagonist properties at subtypes of dopamine D2-like receptor and α1/α2-adrenoceptor J. Pharmacol. Exp. Ther. 303(2),805-814(2002).
4. Schechter, M.D., Rosecrans, J.A., and Glennon, R.A. Comparison of behavioral effects of cathinone, amphetamine and apomorphine Pharmacol. Biochem. Behav. 20(2),181-184(1984).

4H-Dibenzo[de,g]quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride, hydrate (1:1:), (6aR)- Preparation Products And Raw materials

Raw materials

Preparation Products

4H-Dibenzo[de,g]quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride, hydrate (1:1:), (6aR)- Suppliers

Global( 8)Suppliers
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TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
JiangSu Star Science Co.,Ltd 400-400-605-7200-7200 15335295587 sales037@b2star.com China 3761 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826 market@aladdin-e.com China 48461 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19703 58
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd. 025-66061636 18013972705 qqyang@aikonchem.com China 10238 58
Hubei Danding Pharmaceutical Technology Co., Ltd 18917019315 18917019315 18917019315@163.cn China 9437 58

View Lastest Price from 4H-Dibenzo[de,g]quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride, hydrate (1:1:), (6aR)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(-)-Apomorphine hydrochloride hydrate pictures 2024-10-28 (-)-Apomorphine hydrochloride hydrate
58117-94-5
US $739.00-258.00 / mg 10g TargetMol Chemicals Inc.
4H-Dibenzo[de,g]quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride, hydrate (1:1:), (6aR)- 58117-94-5