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ChemicalBook >> CAS DataBase List >>Imidazo[1,2-b]pyridazine-3-carboximidamide, N'-cyano-N-ethyl-6-[(2R,4S)-4-fluoro-2-[3-fluoro-5-(methylthio)phenyl]-1-pyrrolidinyl]-, [C(Z)]-

Imidazo[1,2-b]pyridazine-3-carboximidamide, N'-cyano-N-ethyl-6-[(2R,4S)-4-fluoro-2-[3-fluoro-5-(methylthio)phenyl]-1-pyrrolidinyl]-, [C(Z)]-

CAS No.
2409544-80-3
Chemical Name:
Imidazo[1,2-b]pyridazine-3-carboximidamide, N'-cyano-N-ethyl-6-[(2R,4S)-4-fluoro-2-[3-fluoro-5-(methylthio)phenyl]-1-pyrrolidinyl]-, [C(Z)]-
Synonyms
TRK-IN-17;Imidazo[1,2-b]pyridazine-3-carboximidamide, N'-cyano-N-ethyl-6-[(2R,4S)-4-fluoro-2-[3-fluoro-5-(methylthio)phenyl]-1-pyrrolidinyl]-, [C(Z)]-
CBNumber:
CB412653544
Molecular Formula:
C21H21F2N7S
Molecular Weight:
441.5
MDL Number:
MOL File:
2409544-80-3.mol
Last updated:2025-04-29 09:03:59

Imidazo[1,2-b]pyridazine-3-carboximidamide, N'-cyano-N-ethyl-6-[(2R,4S)-4-fluoro-2-[3-fluoro-5-(methylthio)phenyl]-1-pyrrolidinyl]-, [C(Z)]- Properties

Density 1.41±0.1 g/cm3(Predicted)
pka 2.88±0.30(Predicted)

Imidazo[1,2-b]pyridazine-3-carboximidamide, N'-cyano-N-ethyl-6-[(2R,4S)-4-fluoro-2-[3-fluoro-5-(methylthio)phenyl]-1-pyrrolidinyl]-, [C(Z)]- Chemical Properties,Uses,Production

Uses

TRK-IN-17 is a potent inhibitor of TRK. Tropomyosin-related kinases (Trks) are a family of receptor tyrosine kinases activated by neurotrophins, a group of soluble growth factors including Nerve Growth Factor (NGF), Brain-Derived Neurotrophic Factor (BDNF) and Neurotrophin-3 (NT-3) and Neurotrophin-4/5 (NT-4/5). TRK-IN-17 has the potential for the research of cancer diseases (extracted from patent WO2021148807A1, compound 3)[1].

References

[1] Nicola ROBAS, et al. Pharmaceutical compositions and their uses. Patent WO2021148807A1.

Imidazo[1,2-b]pyridazine-3-carboximidamide, N'-cyano-N-ethyl-6-[(2R,4S)-4-fluoro-2-[3-fluoro-5-(methylthio)phenyl]-1-pyrrolidinyl]-, [C(Z)]- Preparation Products And Raw materials

Raw materials

Preparation Products

Imidazo[1,2-b]pyridazine-3-carboximidamide, N'-cyano-N-ethyl-6-[(2R,4S)-4-fluoro-2-[3-fluoro-5-(methylthio)phenyl]-1-pyrrolidinyl]-, [C(Z)]- Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+8613564774135 zijue.cai@tsbiochem.com United States 19905 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 20032 58

View Lastest Price from Imidazo[1,2-b]pyridazine-3-carboximidamide, N'-cyano-N-ethyl-6-[(2R,4S)-4-fluoro-2-[3-fluoro-5-(methylthio)phenyl]-1-pyrrolidinyl]-, [C(Z)]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
TRK-IN-17 pictures 2025-04-29 TRK-IN-17
2409544-80-3
 US $2140.00-3520.00 / mg 10g TargetMol Chemicals Inc.
  • TRK-IN-17 pictures
  • TRK-IN-17
    2409544-80-3
  • US $2140.00-3520.00 / mg
  • TargetMol Chemicals Inc.
Imidazo[1,2-b]pyridazine-3-carboximidamide, N'-cyano-N-ethyl-6-[(2R,4S)-4-fluoro-2-[3-fluoro-5-(methylthio)phenyl]-1-pyrrolidinyl]-, [C(Z)]- TRK-IN-17 2409544-80-3 C21H21F2N7S