Nudol
- CAS No.
- 86630-46-8
- Chemical Name:
- Nudol
- Synonyms
- Nudol;3,4-Dimethoxy-2,7-phenanthrenediol;2,7-dihydroxy-3,4-dimethoxyphenanthrene;Nudol/2,7-dihydroxy-3,4-dimethoxyphenanthrene
- CBNumber:
- CB23051450
- Molecular Formula:
- C16H14O4
- Molecular Weight:
- 270.27996
- MDL Number:
- MFCD00879816
- MOL File:
- 86630-46-8.mol
| FDA UNII | YB2NXM248V |
|---|
Nudol Chemical Properties,Uses,Production
Uses
Nudol is a phenanthrene compound that has anti-cancer activity. Nudol inhibits cell proliferation, induces cell apoptosis. Nudol inhibits MMP-2M and MMP-9 activity (Ki: 988.9 nM, 1.76 μM, respectively). Nudol can be used in the research of cancers, such as osteosarcoma[1][2].
IC 50
MMP-2: 988.9 nM (Ki); MMP-9: 1.76 μM (Ki)
References
[1] Yuying Zhang, et al. Nudol, a phenanthrene derivative from Dendrobium nobile, induces cell cycle arrest and apoptosis and inhibits migration in osteosarcoma cells. Drug Des Devel Ther. 2019 Jul 29;13:2591-2601. DOI:10.2147/DDDT.S180610
[2] Mohammad Al-Amin, et al. Inhibitory Effect of Dioscorea bulbifera Tubers on the Migration of Triple-Negative Breast Cancer Cells. Breast Cancer Cells. Rev. Bras. Farmacogn. 31, 335–341 (2021).
Nudol Preparation Products And Raw materials
Raw materials
Preparation Products
Nudol Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38668 | 58 | |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Shanghai Winherb Medical Technology Co., Ltd. | 400-186-5138 13341702378 | winherb@126.com | China | 1010 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71826 | 60 |
| Shanghai Uteam Biotechnology Co., Ltd. | 021-36031160 13311776681 | 3338195766@QQ.com | China | 5175 | 55 |
| Shanghai Biological Technology Development Co., Ltd. | 021-69955236-807 13918189704 | chinaruji@chinaruji.com | China | 5176 | 55 |
| Chengdu Push Bio-Technology Co., Ltd. | 028-85370565-229 18080489829 | 3004654993@qq.com | China | 8816 | 60 |
| Chengdu Gupte Biotechnology Co., Ltd. | 13881890404 | 2851503757@qq.com | China | 2283 | 58 |