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ChemicalBook >> CAS DataBase List >>L-Tryptophan, N-[[1-[[(2S)-2-Mercapto-4-Methyl-1-oxopentyl]aMino]cyclopentyl]carbonyl]-

L-Tryptophan, N-[[1-[[(2S)-2-Mercapto-4-Methyl-1-oxopentyl]aMino]cyclopentyl]carbonyl]-

CAS No.
849066-09-7
Chemical Name:
L-Tryptophan, N-[[1-[[(2S)-2-Mercapto-4-Methyl-1-oxopentyl]aMino]cyclopentyl]carbonyl]-
Synonyms
CGS 35601;YFAHICISBQLBQH-OALUTQOASA-N;L-Tryptophan, N-[[1-[[(2S)-2-Mercapto-4-Methyl-1-oxopentyl]aMino]cyclopentyl]carbonyl]-
CBNumber:
CB22668507
Molecular Formula:
C23H31N3O4S
Molecular Weight:
445.57494
MDL Number:
MFCD25977043
MOL File:
849066-09-7.mol
Last updated:2025-04-18 09:51:53

L-Tryptophan, N-[[1-[[(2S)-2-Mercapto-4-Methyl-1-oxopentyl]aMino]cyclopentyl]carbonyl]- Properties

FDA UNII 7D7KS7Y7JY

L-Tryptophan, N-[[1-[[(2S)-2-Mercapto-4-Methyl-1-oxopentyl]aMino]cyclopentyl]carbonyl]- Chemical Properties,Uses,Production

Uses

CGS 35601 is the inhibitor for endothelin-converting enzyme-1 (ECE-1), neutral endopeptidase 24.11 (NEP), and angiotensin-converting enzyme (ACE), with IC50s of 55, 2, and 22 nM, respectively. CGS 35601 suppresses the big endothelin-1 (big ET-1)- and angiotensin I-induced pressor response, and enhances circulation of atrial natriuretic peptide (ANP), regulates the cardiovascular function in SD rats[1].

References

[1] Trapani AJ, et al., CGS 35601 and its orally active prodrug CGS 37808 as triple inhibitors of endothelin-converting enzyme-1, neutral endopeptidase 24.11, and angiotensin-converting enzyme. J Cardiovasc Pharmacol. 2004 Nov;44 Suppl 1:S211-5. DOI:10.1097/01.fjc.0000166237.57077.d6

L-Tryptophan, N-[[1-[[(2S)-2-Mercapto-4-Methyl-1-oxopentyl]aMino]cyclopentyl]carbonyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

L-Tryptophan, N-[[1-[[(2S)-2-Mercapto-4-Methyl-1-oxopentyl]aMino]cyclopentyl]carbonyl]- Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 32285 58
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 19904 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 21356 58

View Lastest Price from L-Tryptophan, N-[[1-[[(2S)-2-Mercapto-4-Methyl-1-oxopentyl]aMino]cyclopentyl]carbonyl]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
CGS 35601 pictures 2024-10-28 CGS 35601
849066-09-7
 US $1520.00-2500.00 / mg 10g TargetMol Chemicals Inc.
  • CGS 35601 pictures
  • CGS 35601
    849066-09-7
  • US $1520.00-2500.00 / mg
  • TargetMol Chemicals Inc.
CGS 35601 L-Tryptophan, N-[[1-[[(2S)-2-Mercapto-4-Methyl-1-oxopentyl]aMino]cyclopentyl]carbonyl]- YFAHICISBQLBQH-OALUTQOASA-N 849066-09-7