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ChemicalBook >> CAS DataBase List >>KVS0001

KVS0001

CAS No.
3056394-59-0
Chemical Name:
KVS0001
Synonyms
KVS0001;Urea, N-[4-[4-[2-[[4-chloro-3-(1-piperazinylsulfonyl)phenyl]amino]-4-pyrimidinyl]-2-pyridinyl]phenyl]-N′-methyl-
CBNumber:
CB214904286
Molecular Formula:
C27H27ClN8O3S
Molecular Weight:
579.08
MDL Number:
MOL File:
3056394-59-0.mol
Last updated:2025-05-19 13:47:13

KVS0001 Properties

Density 1.409±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka 14.002±0.46(predicted)
form Solid
color Light yellow to yellow

KVS0001 Chemical Properties,Uses,Production

Uses

KVS0001 is a potent inhibitor of SMG1 and nonsense mediated decay (NMD) that has anti-tumor activity[1].

References

[1] Ashley L Cook, et al. Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape. bioRxiv. 2023 Dec 29:2023.12.28.573594. DOI:10.1101/2023.12.28.573594

KVS0001 Preparation Products And Raw materials

Raw materials

Preparation Products

KVS0001 Suppliers

Global( 1)Suppliers
Supplier Tel Email Country ProdList Advantage
CAREBIO PHARMA 18501057619 18501057619 jackyfan@rebornpharma.com China 235 58
Supplier Advantage
CAREBIO PHARMA 58
KVS0001 Urea, N-[4-[4-[2-[[4-chloro-3-(1-piperazinylsulfonyl)phenyl]amino]-4-pyrimidinyl]-2-pyridinyl]phenyl]-N′-methyl- 3056394-59-0 KVS0001