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ChemicalBook >> CAS DataBase List >>2(1H)-Pyridinone, 5-(3,5-dimethyl-4-isoxazolyl)-1-(phenylmethyl)-

2(1H)-Pyridinone, 5-(3,5-dimethyl-4-isoxazolyl)-1-(phenylmethyl)-

CAS No.
1616400-50-0
Chemical Name:
2(1H)-Pyridinone, 5-(3,5-dimethyl-4-isoxazolyl)-1-(phenylmethyl)-
Synonyms
ZEN-2759;1-Benzyl-5-(3,5-dimethylisoxazol-4-yl)pyridin-2(1H)-one;2(1H)-Pyridinone, 5-(3,5-dimethyl-4-isoxazolyl)-1-(phenylmethyl)-
CBNumber:
CB15890955
Molecular Formula:
C17 H16 N2 O2
Molecular Weight:
280.32
MDL Number:
MOL File:
1616400-50-0.mol
Last updated:2025-05-16 15:57:46

2(1H)-Pyridinone, 5-(3,5-dimethyl-4-isoxazolyl)-1-(phenylmethyl)- Properties

form Solid
color Off-white to light yellow

2(1H)-Pyridinone, 5-(3,5-dimethyl-4-isoxazolyl)-1-(phenylmethyl)- Chemical Properties,Uses,Production

Description

ZEN-2759 is BRD4(BD1) inhibitor.

Uses

ZEN-2759 is a potent BET (Bromodomain and Extra-Terminal Domain) inhibitor, with IC50 values of 0.23, 0.08 and 0.28 μM for BRD4(BD1), BRD4(BD2), and BRD4(BD1BD2), respectively[1].

IC 50

BRD4 (BD2): 0.08 μM (IC50); BRD4 (BD1): 0.23 μM (IC50); BRD4(BD1BD2): 0.28 μM (IC50)

References

[1] Kharenko OA, et al. Design and Characterization of Novel Covalent Bromodomain and Extra-Terminal Domain (BET) Inhibitors Targeting a Methionine. J Med Chem. 2018 Sep 27;61(18):8202-8211. DOI:10.1021/acs.jmedchem.8b00666

2(1H)-Pyridinone, 5-(3,5-dimethyl-4-isoxazolyl)-1-(phenylmethyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

2(1H)-Pyridinone, 5-(3,5-dimethyl-4-isoxazolyl)-1-(phenylmethyl)- Suppliers

Global( 12)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 32286 58
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 71826 60
Shanghai Chaolan Chemical Technology Center 021-QQ：65489617 15618227136 Sales@ATKchemical.com China 9347 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 62321 58
Suzhou Zhixin Biotechnology Co., Ltd. 0512-65118909 15162312715 sales@szzxbio.com China 2969 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
Hubei wei shi reagent group ltd., company 027-59101766 13125137661 2853877621@qq.com China 8002 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 21356 58
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd 025-58851090 17714375163 2881759498@qq.com China 13011 58

View Lastest Price from 2(1H)-Pyridinone, 5-(3,5-dimethyl-4-isoxazolyl)-1-(phenylmethyl)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ZEN-2759 pictures 2025-05-16 ZEN-2759
1616400-50-0
 US $55.00-197.00 / mg 99.36% 10g TargetMol Chemicals Inc.
  • ZEN-2759 pictures
  • ZEN-2759
    1616400-50-0
  • US $55.00-197.00 / mg
  • 99.36%
  • TargetMol Chemicals Inc.

1616400-50-0(2(1H)-Pyridinone, 5-(3,5-dimethyl-4-isoxazolyl)-1-(phenylmethyl)-)Related Search:

2(1H)-Pyridinone, 5-(3,5-dimethyl-4-isoxazolyl)-1-(phenylmethyl)- ZEN-2759 1-Benzyl-5-(3,5-dimethylisoxazol-4-yl)pyridin-2(1H)-one 1616400-50-0