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ChemicalBook >> CAS DataBase List >>bio-THZ1

bio-THZ1

CAS No.
1604811-14-4
Chemical Name:
bio-THZ1
Synonyms
BIO-THZ1;1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[(2E)-1-[[4-[[[3-[[5-chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]amino]carbonyl]phenyl]amino]-5-methyl-1,10-dioxo-14,17,20-trioxa-5,9,11-triazadocos-2-en-22-yl]hexahydro-2-oxo-, (3aS,4S,6aR)-
CBNumber:
CB15540357
Molecular Formula:
C52H65ClN12O8S
Molecular Weight:
1053.67
MDL Number:
MFCD32201112
MOL File:
1604811-14-4.mol
Last updated:2025-04-18 09:51:43

bio-THZ1 Properties

Density 1.314±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 120 mg/mL (113.89 mM; Need ultrasonic)
pka 12.87±0.70(Predicted)
form Solid
color White to off-white

bio-THZ1 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0101569 bio-THZ1 1604811-14-4 5mg $700 2021-12-16 Buy
ChemScene CS-0101569 bio-THZ1 1604811-14-4 10mg $1200 2021-12-16 Buy
ChemScene CS-0101569 bio-THZ1 1604811-14-4 25mg $2500 2021-12-16 Buy
Product number Packaging Price Buy
CS-0101569 5mg $700 Buy
CS-0101569 10mg $1200 Buy
CS-0101569 25mg $2500 Buy

bio-THZ1 Chemical Properties,Uses,Production

Uses

bio-THZ1 is a biotinylated version of THZ1 and binds irreversibly to CDK7. THZ1 is a selective and potent covalent CDK7 inhibitor with an IC50 of 3.2 nM[1].

References

[1] Kwiatkowski N, et al. Targeting transcription regulation in cancer with a covalent CDK7 inhibitor. Nature. 2014 Jul 31;511(7511):616-20. DOI:10.1038/nature13393

bio-THZ1 Preparation Products And Raw materials

Raw materials

Preparation Products

bio-THZ1 Suppliers

Global( 10)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 32286 58
Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581 sales@chemhifuture.com China 3135 58
Aladdin Scientific 		tp@aladdinsci.com United States 52924 58
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 12952 65
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4621 55
cjbscvictory 13348960310 13348960310 3003867561@qq.com China 10523 58
Nantong Hi-Future Biotechnology Co., Ltd 18051384581 sales@chemhifuture.com China 3217 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9835 58
Changzhou Xianglong Pharmaceutical Technology Co., Ltd., 18915873328 18915873328 296197970@qq.com China 11055 58
Adooq Bioscience LLC 400-025-6535 sales@adooq.cn China 6215 58
BIO-THZ1 1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[(2E)-1-[[4-[[[3-[[5-chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]amino]carbonyl]phenyl]amino]-5-methyl-1,10-dioxo-14,17,20-trioxa-5,9,11-triazadocos-2-en-22-yl]hexahydro-2-oxo-, (3aS,4S,6aR)- 1604811-14-4 C52H65ClN12O8S