Aminoxy-PEG3-acid
- CAS No.
- 1807540-79-9
- Chemical Name:
- Aminoxy-PEG3-acid
- Synonyms
- Aminoxy-PEG3-acid;Aminooxy-PEG3-acid;Aminooxy-PEG3-acid HCl salt;Propanoic acid, 3-[2-[2-[2-(aminooxy)ethoxy]ethoxy]ethoxy]-
- CBNumber:
- CB13062327
- Molecular Formula:
- C9H19NO6
- Molecular Weight:
- 237.25
- MDL Number:
- MFCD26127821
- MOL File:
- 1807540-79-9.mol
Aminoxy-PEG3-acid price More Price(3)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
BroadPharm | BP-21809 | Aminooxy-PEG3-acidHClsalt 98% | 1807540-79-9 | 100mg | $290 | 2021-12-16 | Buy |
Apolloscientific | BIPG1082 | Aminoxy-PEG3-acid | 1807540-79-9 | 100mg | $662 | 2021-12-16 | Buy |
BroadPharm | BP-21809 | Aminooxy-PEG3-acidHClsalt 98% | 1807540-79-9 | 500mg | $750 | 2021-12-16 | Buy |
Aminoxy-PEG3-acid Chemical Properties,Uses,Production
Description
Aminooxy-PEG3-acid HCl salt is a PEG linker containing an aminooxy group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended.
Uses
Aminooxy-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Aminoxy-PEG3-acid Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32239 | 58 |
Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2996 | 58 |
Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6355 | 58 | |
Amatek Scientific Co. Ltd. | 0512-56316828 | info@amateksci.com | China | 28803 | 58 |
Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4838 | 58 |
Alpha Biopharmaceuticals Co., Ltd | 0411-39042497 | sales@alphabiopharm.com | China | 1951 | 58 |
Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 029-86217788 13892832556 | 2440688701@qq.com | China | 1986 | 58 |
View Lastest Price from Aminoxy-PEG3-acid manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-03-23 | Aminooxy-PEG3-acid HCl salt
1807540-79-9
|
US $0.00 / mg | 100mg | >98.00% | 100mg | Xian confluore Biological Technology Co., Ltd. |
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- Aminooxy-PEG3-acid HCl salt
1807540-79-9
- US $0.00 / mg
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
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