Anti-Cadherin 17
- CAS No.
- Chemical Name:
- Anti-Cadherin 17
- Synonyms
- CADH;CAD17;LI-cad;LI-cadherin;Anti-Cadherin 17;Anti-LI-cadherin;Anti-Liver-intestine cadherin;Anti-CDH17 antibody produced in rabbit;Anti-CDH17 antibody produced in chicken;Intestinal peptide-associated transporter HPT-1
- CBNumber:
- CB12875409
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Anti-Cadherin 17 price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | HPA026556 | Anti-CDH17 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab3 | 100μL | $580 | 2024-03-01 | Buy | |
| Sigma-Aldrich | HPA023616 | Anti-CDH17 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2 | 100μL | $547 | 2024-03-01 | Buy | |
| Sigma-Aldrich | HPA023614 | Anti-CDH17 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1 | 100μL | $580 | 2024-03-01 | Buy | |
| Sigma-Aldrich | HPA026556 | Anti-CDH17 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab3 | 25μL | $282 | 2023-06-20 | Buy | |
| Sigma-Aldrich | HPA023616 | Anti-CDH17 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2 | 25μL | $282 | 2023-06-20 | Buy |
Anti-Cadherin 17 Chemical Properties,Uses,Production
Uses
All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.
The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .
General Description
Cadherin-17 is a liver-intestine cadherin protein encoded by the CDH17 gene in humans and belongs to unique member of cadherin superfamily. CDH17 is a non-classical cadherin having seven cadherin domains and a transmembrane domain but lacking the conserved cytoplasmic domain of classical cadherins. Cadherins are cellular adhesion molecules that are crucial for intracellular adhesion. These are considered as potential tumor suppressor genes and any alterations in them may lead to invasion and metastasis of tumor cells. The gene CDH17 is mapped to human chromosome 8q22.1 and contains 18 exons.
Biochem/physiol Actions
The protein encoded by the gene CDH17 (Cadherin-17), also referred to as LI-cadherin, functions in cell adhesion without being dependent on cytoplasmic components, such as catenins or the actin cytoskeleton. Lower expression of this protein due to single nucleotide polymorphisms has been associated with tumor progression and lymph node metastasis of human colorectal carcinoma. It is found to regulate the signaling function of α2β1 integrin in cell adhesion and proliferation in liver metastatic cancer cells.
Anti-Cadherin 17 Preparation Products And Raw materials
Raw materials
Preparation Products
Anti-Cadherin 17 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Merck KGaA | (+86) 21 2033 8288 | sigmaname@qq.com | CHINA | 292394 | 58 |
| Supplier | Advantage |
|---|---|
| Merck KGaA | 58 |