(±)14(15)-EET-SI
- CAS No.
- 218461-97-3
- Chemical Name:
- (±)14(15)-EET-SI
- Synonyms
- (±)14(15)-EET-SI;(±)14(15)-EET-SI;5,8,11-Tridecatrienamide, N-(methylsulfonyl)-13-(3-pentyl-2-oxiranyl)-, (5Z,8Z,11Z)-
- CBNumber:
- CB12589791
- Molecular Formula:
- C21H35NO4S
- Molecular Weight:
- 397.57
- MDL Number:
- MFCD12912332
- MOL File:
- 218461-97-3.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H302-H319-H336 | |||||||||
| Precautionary statements | P210-P240-P241-P242-P243-P261-P264-P270-P271-P280-P301+P312-P330-P303+P361+P353-P304+P340-P305+P351+P338-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501 | |||||||||
| NFPA 704 |
|
(±)14(15)-EET-SI price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 10009286 | (±)14(15)-EET-SI ≥95% | 218461-97-3 | 25μg | $81 | 2024-03-01 | Buy |
| Cayman Chemical | 10009286 | (±)14(15)-EET-SI ≥95% | 218461-97-3 | 50μg | $152 | 2024-03-01 | Buy |
| Cayman Chemical | 10009286 | (±)14(15)-EET-SI ≥95% | 218461-97-3 | 100μg | $286 | 2024-03-01 | Buy |
| American Custom Chemicals Corporation | LIP0000668 | N-(METHYLSULFONYL)-13-(3-PENTYLOXIRANYL)-5Z,8Z,11Z-TRIDECATRIENAMIDE 95.00% | 218461-97-3 | 5MG | $496.39 | 2021-12-16 | Buy |
(±)14(15)-EET-SI Chemical Properties,Uses,Production
Description
Arachidonic acid is metabolized in the vascular endothelium to epoxytrienoic acids (EETs or EpETrEs) by cytochrome P450 enzymes. The EETs are released in response to acetylcholine, bradykinin, arachidonic acid, or cyclic stretch.1 (±)14(15)-EET-SI is the methyl sulfonamide analog of 14(15)-EET. This substitution results in a metabolically more stable compound because it is not sensitive to β-
Uses
14,15-EET-SI is a sulfonimide (SI) analog metabolized from 14,15-EET, which is also an effective mitogen. 14,15-EET-SI can stimulate the incorporation of [3H] thymidine, activate pp60c-src and initiate the tyrosine kinase cascade, mediating their mitotic effects. Additionally, 14,15-EET-SI can increase cell proliferation as well as the expression of c-fos and egr-1 mRNA[1].
References
1. Gauthier, K.M., Falck, J.R., Reddy, L.M., et al. 14,15-
2. Chen, J.K., Falck, J.R., Reddy, K.M., et al. Epoxyeicosatrienoic acids and their sulfonimide derivatives stimulate tyrosine phosphorylation and induce mitogenesis in renal epithelial cells J. Biol. Chem. 273(44),29254-29261(1998).
(±)14(15)-EET-SI Preparation Products And Raw materials
Raw materials
Preparation Products
(±)14(15)-EET-SI Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 32286 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6777 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8140 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24898 | 58 |
| Hubei Danding Pharmaceutical Technology Co., Ltd | 17701422016 17701422016 | 3587493084@qq.com | China | 8892 | 58 |
| Cayman Chemical Company | 800-364-9897 | sales@caymanchem.com | China | 6838 | 58 |
| Santa Cruz Biotechnology Inc | 021-60936350 | scbt@scbt.com | China | 6594 | 58 |
View Lastest Price from (±)14(15)-EET-SI manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-24 | (±)14(15)-EET-SI
218461-97-3
|
US $380.00 / μg | 10g | TargetMol Chemicals Inc. |
-
- (±)14(15)-EET-SI
218461-97-3
- US $380.00 / μg
- TargetMol Chemicals Inc.