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ChemicalBook >> CAS DataBase List >>Ethane-1,1,2,2-d4-sulfonic acid, 2-[[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-

Ethane-1,1,2,2-d4-sulfonic acid, 2-[[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-

CAS No.
2573035-17-1
Chemical Name:
Ethane-1,1,2,2-d4-sulfonic acid, 2-[[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-
Synonyms
Ethane-1,1,2,2-d4-sulfonic acid, 2-[[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-
CBNumber:
CB112797830
Molecular Formula:
C26H45NO6S
Molecular Weight:
499.71
MDL Number:
MOL File:
2573035-17-1.mol
Last updated:2025-04-18 09:51:35

Ethane-1,1,2,2-d4-sulfonic acid, 2-[[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl]amino]- Chemical Properties,Uses,Production

Uses

Tauroursodeoxycholate-d4-1 is the deuterium labeled Tauroursodeoxycholate. Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

References

[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Kim SY, et al. Tauroursodeoxycholate (TUDCA) inhibits neointimal hyperplasia by suppression of ERK viaPKCα-mediated MKP-1 induction. Cardiovasc Res. 2011 Nov 1;92(2):307-16. DOI:10.1093/cvr/cvr219
[3] Qin Y, et al. Tauroursodeoxycholic Acid Attenuates Angiotensin II Induced Abdominal Aortic Aneurysm Formation in Apolipoprotein E-deficient Mice by Inhibiting Endoplasmic Reticulum Stress. Eur J Vasc Endovasc Surg. 2017 Mar;53(3):337-345. DOI:10.1016/j.ejvs.2016.10.026

Ethane-1,1,2,2-d4-sulfonic acid, 2-[[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl]amino]- Preparation Products And Raw materials

Raw materials

Preparation Products

Ethane-1,1,2,2-d4-sulfonic acid, 2-[[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl]amino]- Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
ChengDu SinoStandards Bio-Tech Co.,Ltd. ， 028-83243028 19136088901 sinostandards@163.com China 4977 58
LGC Science (Shanghai) Ltd. 17717235263 cindy.yang@lgcgroup.com China 17730 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
Cayman Chemical Company 800-364-9897 sales@caymanchem.com China 27736 58
Ethane-1,1,2,2-d4-sulfonic acid, 2-[[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl]amino]- 2573035-17-1