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ChemicalBook >> CAS DataBase List >>Lenacapavir

Lenacapavir

CAS No.
2189684-44-2
Chemical Name:
Lenacapavir
Synonyms
Lenacapavir;1H-Cyclopropa[3,4]cyclopenta[1,2]pyrazole-1-acetamide, N-[(1S)-1-[3-[4-chloro-3-[(methylsulfonyl)amino]-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl]-6-[3-methyl-3-(methylsulfonyl)-1-butyn-1-yl]-2-pyridinyl]-2-(3,5-difluorophenyl)ethyl]-5,5-difluoro-3b,4,4a,5-tetrahydro-3-(trifluoromethyl)-, (3bS,4aR)-;GS-6207;Sunitinib Impurity 72;13C,2H3]-Lenacapavir , isomeric mixture;13C,2H3]-Lenacapavir (Major),isomers mixture;MT-4,Inhibitor,antiretroviral,Lenacapavir,inhibit,GS 6207,capsid,Human immunodeficiency virus,HIV,GS6207,HIV-1,PBMCs;1H-Cyclopropa[3,4]cyclopenta[1,2-c]pyrazole, N-[(1S)-1-[3-[4-chloro-3-[(methylsulfonyl)amino]-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl]-6-[3-methyl-3-(methylsulfonyl)-1-butyn-1-yl]-2-pyridinyl]-2-(3,5-difluorophenyl)ethyl]-5,5-difluoro-3b,4,4a,5-tetrahydro-3-(trifluoromethyl)-, (3bS,4aR)-;N-((S)-1-(3-(4-Chloro-3-(methylsulfonamido)-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl)-6-(3-methyl-3-(methylsulfonyl)but-1-yn-1-yl)pyridin-2-yl)-2-(3,5-difluorophenyl)ethyl)-2-((3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)acetamide
CBNumber:
CB05544792
Molecular Formula:
C39H32ClF10N7O5S2
Molecular Weight:
968.28
MDL Number:
MFCD32701907
MOL File:
2189684-44-2.mol
Last updated:2025-05-27 21:43:27

Lenacapavir Properties

Density 1.62±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: 250 mg/mL (258.19 mM)
form Solid
pka 4.63±0.30(Predicted)
color White to light yellow
FDA UNII A9A0O6FB4H

Lenacapavir price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0094695 Lenacapavir 98.49% 2189684-44-2 5mg $950 2021-12-16 Buy
ChemScene CS-0094695 Lenacapavir 98.49% 2189684-44-2 10mg $1600 2021-12-16 Buy
ChemScene CS-0094695 Lenacapavir 98.49% 2189684-44-2 25mg $2800 2021-12-16 Buy
ChemScene CS-0094695 Lenacapavir 98.49% 2189684-44-2 50mg $4200 2021-12-16 Buy
ChemScene CS-0094695 Lenacapavir 98.49% 2189684-44-2 100mg $6900 2021-12-16 Buy
Product number Packaging Price Buy
CS-0094695 5mg $950 Buy
CS-0094695 10mg $1600 Buy
CS-0094695 25mg $2800 Buy
CS-0094695 50mg $4200 Buy
CS-0094695 100mg $6900 Buy

Lenacapavir Chemical Properties,Uses,Production

Description

HIV-1 capsid inhibitor GS-6207 (lenacapavir) is a drug being developed by Gilead Sciences, Inc. It is a first-in-class, oral HIV-1 capsid inhibitor.

Uses

Lenacapavir can be useful in capsid inhibition in multidrug-resistant HIV-1 infection.

Application

Lenacapasvir was first approved in the European Union in 2022 for use in combination with other antiretroviral drugs to treat multidrug-resistant adults with HIV and those who are unable to establish a suppressive antiviral regimen. Subsequently, the drug also received similar approvals in Canada and the United States. Lenacapasvir is available as an oral and injectable therapy and is a long-acting, extended-release drug for the treatment of HIV-1. When used in combination with other antiretroviral drugs, it may only need to be administered once every 6 months, aiming to improve patient compliance and medication adherence.

Mechanism of action

Lenacapasvir works by inhibiting the HIV-1 capsid protein, a protein shell that encapsulates the viral genetic material and is involved in multiple stages of the HIV life cycle. Lenacapasvir is the first drug approved to inhibit the HIV-1 capsid, providing a new treatment option for adults with multidrug-resistant HIV infection.

IC 50

HIV-1

Lenacapavir Preparation Products And Raw materials

Raw materials

Preparation Products

Lenacapavir Suppliers

Global( 91)Suppliers
Supplier Tel Email Country ProdList Advantage
S&Y Biochem Co.,Ltd
+8617774091612 marketing@sybiochem.com China 189 58
Unibest Industrial Co.,Ltd.
+86-0574-27855777 +8618758850676 info@unibestcn.com China 238 58
ChemExpress
+86-021-58950125 +86-021-58950125; info@chemexpress.com China 785 58
Jinan Jianfeng Chemical Co., Ltd 		+86-0531-88110457 +86-15562555968 info@pharmachemm.com China 331 58
Shanghai Daken Advanced Materials Co.,Ltd 		+86-2158073036 info@dakenam.com China 19874 58
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 8497 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		+86-021-61551413 +8618813727289 contact@trustwe.com China 5745 58
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 32284 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49734 58

View Lastest Price from Lenacapavir manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Lenacapavir pictures 2025-06-05 Lenacapavir
2189684-44-2
 US $0.00-0.00 / mg 1mg 99% 5000 Jinan Jianfeng Chemical Co., Ltd
GS-6207 pictures 2025-06-05 GS-6207
2189684-44-2
 US $0.00 / mg 1mg 99% 5000 Jinan Jianfeng Chemical Co., Ltd
Lenacapavir pictures 2025-05-27 Lenacapavir
2189684-44-2
 US $333.00-1130.00 / mg 99.61% 10g TargetMol Chemicals Inc.
  • Lenacapavir pictures
  • Lenacapavir
    2189684-44-2
  • US $0.00-0.00 / mg
  • 99%
  • Jinan Jianfeng Chemical Co., Ltd
  • GS-6207 pictures
  • GS-6207
    2189684-44-2
  • US $0.00 / mg
  • 99%
  • Jinan Jianfeng Chemical Co., Ltd
  • Lenacapavir pictures
  • Lenacapavir
    2189684-44-2
  • US $333.00-1130.00 / mg
  • 99.61%
  • TargetMol Chemicals Inc.

Lenacapavir Spectrum

GS-6207 1H-Cyclopropa[3,4]cyclopenta[1,2]pyrazole-1-acetamide, N-[(1S)-1-[3-[4-chloro-3-[(methylsulfonyl)amino]-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl]-6-[3-methyl-3-(methylsulfonyl)-1-butyn-1-yl]-2-pyridinyl]-2-(3,5-difluorophenyl)ethyl]-5,5-difluoro-3b,4,4a,5-tetrahydro-3-(trifluoromethyl)-, (3bS,4aR)- Lenacapavir 13C,2H3]-Lenacapavir , isomeric mixture MT-4,Inhibitor,antiretroviral,Lenacapavir,inhibit,GS 6207,capsid,Human immunodeficiency virus,HIV,GS6207,HIV-1,PBMCs 1H-Cyclopropa[3,4]cyclopenta[1,2-c]pyrazole, N-[(1S)-1-[3-[4-chloro-3-[(methylsulfonyl)amino]-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl]-6-[3-methyl-3-(methylsulfonyl)-1-butyn-1-yl]-2-pyridinyl]-2-(3,5-difluorophenyl)ethyl]-5,5-difluoro-3b,4,4a,5-tetrahydro-3-(trifluoromethyl)-, (3bS,4aR)- 13C,2H3]-Lenacapavir (Major),isomers mixture N-((S)-1-(3-(4-Chloro-3-(methylsulfonamido)-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl)-6-(3-methyl-3-(methylsulfonyl)but-1-yn-1-yl)pyridin-2-yl)-2-(3,5-difluorophenyl)ethyl)-2-((3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)acetamide Sunitinib Impurity 72 2189684-44-2 C39H32ClF10N7O5S2 API