ChemicalBook >> CAS DataBase List >>Ethanone, 1-[6,7-dihydro-4-(6-methyl-2-pyridinyl)thieno[3,2-c]pyridin-5(4H)-yl]-2-[(2-methylbutyl)amino]-, hydrochloride (1:2)
Ethanone, 1-[6,7-dihydro-4-(6-methyl-2-pyridinyl)thieno[3,2-c]pyridin-5(4H)-yl]-2-[(2-methylbutyl)amino]-, hydrochloride (1:2)
![Ethanone, 1-[6,7-dihydro-4-(6-methyl-2-pyridinyl)thieno[3,2-c]pyridin-5(4H)-yl]-2-[(2-methylbutyl)amino]-, hydrochloride (1:2) Structure](CAS/20211123/GIF/2320262-09-5.gif)
- CAS No.
- 2320262-09-5
- Chemical Name:
- Ethanone, 1-[6,7-dihydro-4-(6-methyl-2-pyridinyl)thieno[3,2-c]pyridin-5(4H)-yl]-2-[(2-methylbutyl)amino]-, hydrochloride (1:2)
- Synonyms
- Ethanone, 1-[6,7-dihydro-4-(6-methyl-2-pyridinyl)thieno[3,2-c]pyridin-5(4H)-yl]-2-[(2-methylbutyl)amino]-, hydrochloride (1:2)
- CBNumber:
- CB010494709
- Molecular Formula:
- C20H28ClN3OS
- Molecular Weight:
- 393.97
- MDL Number:
- MOL File:
- 2320262-09-5.mol
Last updated:2023-04-23 13:52:06
Ethanone, 1-[6,7-dihydro-4-(6-methyl-2-pyridinyl)thieno[3,2-c]pyridin-5(4H)-yl]-2-[(2-methylbutyl)amino]-, hydrochloride (1:2) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 21101 | RU-SKI 201 (hydrochloride) ≥95% | 2320262-09-5 | 1 mg | $61 | 2024-03-01 | Buy |
| Cayman Chemical | 21101 | RU-SKI 201 (hydrochloride) ≥95% | 2320262-09-5 | 5 mg | $264 | 2024-03-01 | Buy |
| Cayman Chemical | 21101 | RU-SKI 201 (hydrochloride) ≥95% | 2320262-09-5 | 10 mg | $468 | 2024-03-01 | Buy |
Ethanone, 1-[6,7-dihydro-4-(6-methyl-2-pyridinyl)thieno[3,2-c]pyridin-5(4H)-yl]-2-[(2-methylbutyl)amino]-, hydrochloride (1:2) Chemical Properties,Uses,Production
Description
RU-SKI 201 is an inhibitor of hedgehog acyltransferase (Hhat; IC50 = 0.2 μM for recombinant enzyme).1 It inhibits palmitoylation of sonic hedgehog (Shh) in Shh-overexpressing HEK293 cells with a tagging IC50 (TC50) value of 0.87 μM. RU-SKI 201 inhibits hedgehog (Hh) signaling in H520, PANC-1, and MCF-7 cancer cells co-cultured with Shh-Light2 cells (IC50s = 4.8, 7.8, and 8.5 μM, respectively).
References
1. Rodgers, U.R., Lanyon-Hogg, T., Masumoto, N., et al. Characterization of hedgehog acyltransferase inhibitors identifies a small molecule probe for hedgehog signaling by cancer cells ACS Chem. Biol. 11(12),3256-3262(2016).
Ethanone, 1-[6,7-dihydro-4-(6-methyl-2-pyridinyl)thieno[3,2-c]pyridin-5(4H)-yl]-2-[(2-methylbutyl)amino]-, hydrochloride (1:2) Preparation Products And Raw materials
Raw materials
Preparation Products
Ethanone, 1-[6,7-dihydro-4-(6-methyl-2-pyridinyl)thieno[3,2-c]pyridin-5(4H)-yl]-2-[(2-methylbutyl)amino]-, hydrochloride (1:2) Suppliers
Global( 4)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9806 | 58 |
| Jinan Jiuli Biotechnology Co. , Ltd. | 15865264761 | 486064515@qq.com | China | 4672 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19703 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai EFE Biological Technology Co., Ltd. | 58 |
| Jinan Jiuli Biotechnology Co. , Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |
Ethanone, 1-[6,7-dihydro-4-(6-methyl-2-pyridinyl)thieno[3,2-c]pyridin-5(4H)-yl]-2-[(2-methylbutyl)amino]-, hydrochloride (1:2)
2320262-09-5