Identification | More | [Name]
N-Succinimidyl 3-maleimidopropionate | [CAS]
55750-62-4 | [Synonyms]
3-MALEIMIDOPROPIONIC ACID N-HYDROXYSUCCINIMIDE ESTER 3-MALEIMIDOPROPIONIC ACID N-SUCCINIMIDYL ESTER MALEIMIDOPROPIONIC ACID N-HYDROXYSUCCINIMIDE ESTER MPS N-(3-MALEIMIDOPROPIONYLOXY)SUCCINIMIDE N-MALEOYL-BETA-ALANINE N'-HYDROXYSUCCINIMIDE ESTER N-SUCCINIMIDYL 3-MALEIMIDOPROPIONATE 3-Maleidopropionic acid N-hydroxysuccynimide ester (SMP) B-MALEIMIDOPROPIONIC ACID N-*HYDROXYSUCCINIMIDE ESTE Cross-linkingReagent N-Succinimidyl3-maleinimidopropionate N-SUCCINIMIDYL3-MALEIMIDOPROPIONATE[CROSS-LINKINGREAGENT] 3-Maleimidopropionic acid succinimidyl ester 3-Maleimidopropionic acid NHS 3-(Maleimido)propionic acid N-succinimidyl ester, BMPS, N-(3-Maleimidopropionyloxy)succinimide, N-Maleoyl-β-alanine Nμ-hydroxysuccinimide ester, N-Succinimidyl 3-maleimidopropionate N-(3-Maleimidopropionyloxy)succinimide, N-Succinimidyl 3-maleimidopropionate, BMPS, N-Maleoyl-β-alanine Nμ-hydroxysuccinimide ester, N-Maleoyl-β-alanine N-hydroxysuccinimide ester 1-[3-[(2,5-Dioxopyrrolidin-1-yl)oxy]-3-oxopropyl]-1H-pyrrole-2,5-dione 2,5-Dioxo-2,5-dihydro-1H-pyrrole-1-propionic acid 2,5-dioxo-1-pyrrolidinyl ester 2,5-Dioxo-3-pyrroline-1-propionic acid 2,5-dioxopyrrolidine-1-yl ester 2,5-Dioxo-3-pyrroline-1-propionic acid succinimidyl ester | [EINECS(EC#)]
627-755-4 | [Molecular Formula]
C11H10N2O6 | [MDL Number]
MFCD00043141 | [Molecular Weight]
266.21 | [MOL File]
55750-62-4.mol |
Chemical Properties | Back Directory | [Melting point ]
168-170 °C(lit.) | [Boiling point ]
448.8±47.0 °C(Predicted) | [density ]
1.55±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C
| [solubility ]
Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
-2.39±0.20(Predicted) | [color ]
White to Light Brown | [Water Solubility ]
Insoluble in water. | [Sensitive ]
Moisture Sensitive | [Usage]
A short, sulfhydryl and amino reactive heterobifunctional crosslinking reagent. Also used in immunodiagnostics.
Spacer Arm: 6.9 Angstrom | [BRN ]
1492578 | [CAS DataBase Reference]
55750-62-4(CAS DataBase Reference) |
Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R37:Irritating to the respiratory system. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [WGK Germany ]
3
| [F ]
10-21 | [HS Code ]
29280000 |
Hazard Information | Back Directory | [Description]
3-Maleimido-propionic NHS ester contains a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. | [Chemical Properties]
White to off-white solid | [Uses]
3-Maleimidopropionic acid N-hydroxysuccinimide ester is a reagent that is widely used for generating stable maleimide-activated carrier proteins that can spontaneously react with sulfhydryls. Alternatively these relatively stable maleimide-activated intermediates may be lyophilized and stored for later conjugation to a hapten. | [Uses]
A short, sulfhydryl and amino reactive heterobifunctional crosslinking reagent, N-Succinimidyl 3-maleimidopropionate can also been used in immunodiagnostics.
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