Anti-eIF-2B GDP-GTP exchange factor subunit epsilon, Anti-eIF2Bε antibody produced in rabbit, Anti-Eukaryotic translation initiation factor 2B, ε, Anti-Eukaryotic translation initiation factor 2B, subunit 5 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Anti-eIF2Bε antibody produced in rabbit is suitable for indirect immunofluorescence (at a dilution of 1:500-1:1,000 using paraformaldehyde fixed NIH-3T3 cells) and western blotting at a dilution of 1:500-1:1,000 using Rat1 or HEK-293T cell lysates.
Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about us and Yale Center for High Throughput Cell Biology partnership, visit
sigma.com/htcb-if.
Biochem/physiol Actions
Translation initiation factor eIF-2B subunit ε is a protein encoded by the EIF2B5 gene in humans. The eIF2B is composed of five subunits α, β, γ, δ and ε, within which the ε subunit is responsible for catalyzing the guanine exchange reaction. Defect in any of these 5 subunits leads to diseases. Mutation in the subunit of eIF2B is associated with an autosomal recessive leukoencephalopathy called Vanishing white matter (VWM).
Anti-eIF-2B GDP-GTP exchange factor subunit epsilon, Anti-eIF2Bε antibody produced in rabbit, Anti-Eukaryotic translation initiation factor 2B, ε, Anti-Eukaryotic translation initiation factor 2B, subunit 5 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte