RNAIII-inhibiting peptide(TFA)
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RNAIII-inhibiting peptide(TFA)性質、用途與生產(chǎn)工藝
生物活性
RNAIII-inhibiting peptide(TFA) 是一種有效的 Staphylococcus aureus 多肽抑制劑,在蜂窩組織炎、角膜炎、化膿性關節(jié)炎、骨肌炎和乳腺炎等疾病中有功效。靶點
Staphylococcus aureus
體外研究
RNAIII-inhibiting peptide(TFA) is a potent inhibitor of Staphylococcus aureus . RNAIII-inhibiting peptide (RIP) inhibits the synthesis of both RNAII and RNAIII, while RAP activates in wild type S. aureus cells. RNAIII-inhibiting peptide (5 μg/10 6 cells) potently reduces bacterial cell adhesion to HEp2 cells in the absence of serum, but with slight overall reduction the presence of serum. RNAIII-inhibiting peptide inhibits while RAP induces the phosphorylation of TRAP.
體內(nèi)研究
RNAIII-inhibiting peptide (20 mg/kg, i.v.) decreases lethality in mice challenged with S. aureus ATCC 25923, with the lethality rate of 70%, and when combined with cefazolin, imipenem, vancomycin, the rates are 20%, 15% and 10%. RNAIII-inhibiting peptide (20 mg/kg, i.v.) also causes decreased lethality in mice challenged with S. aureus Smith, with the lethality rate of 75%, and the lethality rate decreases to 30%, 10% and 10% when combined with cefazolin, imipenem, vancomycin.
RNAIII-inhibiting peptide(TFA) 上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
RNAIII-inhibiting peptide(TFA) 試劑級價格
RNAIII-inhibiting peptide(TFA) 生產(chǎn)廠家
供應商 | 聯(lián)系電話 | 電子郵件 | 國家 | 產(chǎn)品數(shù) | 優(yōu)勢度 |
---|---|---|---|---|---|
Creative Peptides | info@creative-peptides.com | 美國 | 6083 | 56 | |
TargetMol中國(陶術生物) | 15002134094 | marketing@targetmol.cn | 中國 | 21356 | 58 |
生工生物工程(上海)股份有限公司 | 400-821-026 | Sales@sangon.com | 中國 | 6710 | 58 |
TargetMol Chemicals Inc. | support@targetmol.com | 美國 | 38669 | 58 |
RNAIII-inhibiting peptide(TFA) 相關搜索:
- 抑制劑
- RNAIII inhibiting peptide TFA,RNAIIIinhibiting peptide TFA
- RNAIII-inhibiting peptide(TFA)
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