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SP-8-CPT-CAMPS

SP-8-CPT-CAMPS, 129693-13-6, 結(jié)構(gòu)式
SP-8-CPT-CAMPS
CAS號(hào):
129693-13-6
英文名:
8-(4-CHLOROPHENYLTHIO) ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT
英文別名:
Sp-8-CPT-cAMPS;SP-8-PCPT-CAMPS;SP-8-PCPT-CAMPS, NA;SP-8-CPT-CAMPS SODIUM SALT;8-(4-Chlorophenylthio)-adenosine-3'',5''-cyclic monophosphothioate sodium sal;Adenosine, 8-[(4-chlorophenyl)thio]-, cyclic 3',5'-[hydrogen (S)-phosphorothioate];8-(4-CHLOROPHENYLTHIO) ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT;ADENOSINE 3',5'-CYCLIC MONOPHOSPHOROTHIOATE, 8-(4-CHLOROPHENYLTHIO)-, SP-ISOMER, SODIUM SALT;8-(4-chlorophenylthio)adenosine-3’,5’-cyclicmonophosphorothioate,rp-isomer(rp-8-cpt-camps),sodi
中文名:
SP-8-CPT-CAMPS
中文別名:
CBNumber:
CB8246174
分子式:
C16H14ClN5NaO5PS2
分子量:
509.86
MOL File:
129693-13-6.mol

SP-8-CPT-CAMPS化學(xué)性質(zhì)

儲(chǔ)存條件:
−70°C
溶解度:
H2O: >1 mg/mL
形態(tài):
solid
安全信息
WGK Germany: 3

SP-8-CPT-CAMPS性質(zhì)、用途與生產(chǎn)工藝

生物活性

Sp-8-CPT-cAMPS，一種 cAMP 類似物，是 cAMP 依賴性蛋白激酶 A PKA I 和 PKA II 的有效和選擇性的激活劑。Sp-8-CPT-cAMPS 優(yōu)先選擇 RI 的位點(diǎn) A 與 RII 的位點(diǎn) B。

靶點(diǎn)

PKA

體外研究

Sp-8-CPT-cAMPS (100 μM; 24 h) enhances the IL-1β-stimulated nitrite release, and increases the release ofnitrite by vascular smooth muscle cells by 3 fold in the absence of IL-1β in vascular smooth muscle cells.
Sp-8-CPT-cAMPS (100 μM; 24 h) increases IL-1β-induced expression of iNOS protein in rat aortic smooth muscle cells.
Sp-8-CPT-cAMPS (10?μM; 30?min) exhibits anti-spasmogenic activity on ACh-induced tension development in guinea-pig trachealis.

SP-8-CPT-CAMPS 上下游產(chǎn)品信息

上游原料

下游產(chǎn)品

SP-8-CPT-CAMPS 生產(chǎn)廠家

全球有 13家供應(yīng)商   SP-8-CPT-CAMPS國(guó)內(nèi)生產(chǎn)廠家
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BOC Sciences 16314854226; +16314854226 inquiry@bocsci.com 美國(guó) 19654 58
BOC Sciences 16314854226 inquiry@bocsci.com 美國(guó) 9713 58
上海立崎生物醫(yī)學(xué)研究中心 18014399201 sales@chemlab-tachizaki.com 中國(guó) 2666 58
TargetMol中國(guó)（陶術(shù)生物） 15002134094 marketing@targetmol.cn 中國(guó) 19699 58
Enzo Biochem Inc 80-Enzo Biochem Inc. 18009420430 info-usa@enzolifesciences.com 中國(guó) 124812 58
 

129693-13-6, SP-8-CPT-CAMPS 相關(guān)搜索:

  • 抑制劑
  • 129693-13-6
  • Adenosine, 8-[(4-chlorophenyl)thio]-, cyclic 3',5'-[hydrogen (S)-phosphorothioate]
  • Sp-8-CPT-cAMPS
  • SP-8-PCPT-CAMPS, NA
  • SP-8-CPT-CAMPS SODIUM SALT
  • ADENOSINE 3',5'-CYCLIC MONOPHOSPHOROTHIOATE, 8-(4-CHLOROPHENYLTHIO)-, SP-ISOMER, SODIUM SALT
  • 8-(4-CHLOROPHENYLTHIO) ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT
  • 8-(4-Chlorophenylthio)-adenosine-3'',5''-cyclic monophosphothioate sodium sal
  • SP-8-PCPT-CAMPS
  • 8-(4-chlorophenylthio)adenosine-3’,5’-cyclicmonophosphorothioate,rp-isomer(rp-8-cpt-camps),sodi
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