卡維地洛葡糖苷酸
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- CAS號(hào):
- 114869-83-9
- 英文名:
- Carvedilol b-D-Glucuronide
- 英文別名:
- Carvedilol-D-Glucuronide;(Glucopyranosiduronic Acid;Carvedilol b-D-Glucuronide;Carvedilol β-D-glucuronide;Carvedilol Glucosidic Acid;(R,S)-Carvedilol Glucuronide;Carvedilol-beta-D-glucuronide;(R,S)-Carvedilol O-β-D-glucuronide;Carvedilol β-D-Glucuronide (mixture of diasteromers);Carvedilol 2-D-Glucuronide (mixture of diasteromers)
- 中文名:
- 卡維地洛葡糖苷酸
- 中文別名:
- 卡維地洛葡糖苷酸;卡維地洛-Β-D-葡糖苷酸;卡維地洛-D-葡萄糖醛酸苷;卡維地洛BETA-D-葡糖苷酸;卡維地洛葡糖苷酸(卡維地洛雜質(zhì)38);(R,S)-卡維地洛O-Β-D-葡糖醛酸;(R,S)-卡維地洛 O-Β-D-葡萄糖苷酸;(R,S)-卡維地洛O-Β-D-葡萄糖醛酸苷;CARVEDILOL-Β-D-GLUCURONIDE[干冰運(yùn)輸];(2S,3S,4S,5R,6R)-6-((1-((9H-咔唑-4-基)氧基)-3-((2-(2-甲氧基苯氧基)乙基)氨基)丙-2- 基)氧基)-3,4,5-三羥基四氫-2H-吡喃-2-羧酸 (卡維地洛雜質(zhì))
- CBNumber:
- CB71176192
- 分子式:
- C30H34N2O10
- 分子量:
- 582.6
- MOL File:
- 114869-83-9.mol
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卡維地洛葡糖苷酸化學(xué)性質(zhì)
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熔點(diǎn):
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143-146°C
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沸點(diǎn):
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880.9±65.0 °C(Predicted)
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密度:
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1.45±0.1 g/cm3(Predicted)
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儲(chǔ)存條件:
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Hygroscopic, -20°C Freezer, Under Inert Atmosphere
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溶解度:
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Aqueous Base (Slightly), DMSO (Slightly), Methanol (Slightly, Sonicated)
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形態(tài):
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Solid
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酸度系數(shù)(pKa):
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2.78±0.70(Predicted)
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顏色:
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White to Beige
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卡維地洛葡糖苷酸性質(zhì)、用途與生產(chǎn)工藝
卡維地洛葡糖苷酸 是 Carvedilol (HY-B0006) 的代謝物。Carvedilol (BM 14190) 是腎上腺素受體 β 和 α-1 的拮抗劑。Carvedilol 抑制脂質(zhì)過(guò)氧化，IC50 為 5 μM。Carvedilol 是一種抗高血壓藥物，可用于治療心絞痛和充血性心力衰竭。Carvedilol 可以誘導(dǎo)自噬 (autophagy)， 并可抑制 NLRP3 炎癥小體。
卡維地洛葡糖苷酸
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
卡維地洛葡糖苷酸
生產(chǎn)廠(chǎng)家
114869-83-9, 卡維地洛葡糖苷酸 相關(guān)搜索:
- Pharmaceuticals
- Metabolites & Impurities
- Intermediates & Fine Chemicals
- Glucuronides
- 抑制劑
- C30H34N2O10
- (R,S)-卡維地洛O-Β-D-葡糖醛酸
- (R,S)-卡維地洛 O-Β-D-葡萄糖苷酸
- 卡維地洛葡糖苷酸(卡維地洛雜質(zhì)38)
- (2S,3S,4S,5R,6R)-6-((1-((9H-咔唑-4-基)氧基)-3-((2-(2-甲氧基苯氧基)乙基)氨基)丙-2- 基)氧基)-3,4,5-三羥基四氫-2H-吡喃-2-羧酸 (卡維地洛雜質(zhì))
- 卡維地洛-Β-D-葡糖苷酸
- (R,S)-卡維地洛O-Β-D-葡萄糖醛酸苷
- 卡維地洛BETA-D-葡糖苷酸
- CARVEDILOL-Β-D-GLUCURONIDE[干冰運(yùn)輸]
- 卡維地洛-D-葡萄糖醛酸苷
- 卡維地洛葡糖苷酸
- 114869-83-9
- (2S,3S,4S,5R,6R)-6-((1-((9H-Carbazol-4-yl)oxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)propan-2-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid (Carvedilol Impurity)
- Carvedilol Glucosidic Acid
- β-D-Glucopyranosiduronic acid, 2-(9H-carbazol-4-yloxy)-1-[[[2-(2-methoxyphenoxy)ethyl]amino]methyl]ethyl
- Carvedilol-beta-D-glucuronide
- (R,S)-Carvedilol Glucuronide
- Carvedilol 2-D-Glucuronide (mixture of diasteromers)
- (R,S)-Carvedilol O-β-D-glucuronide
- (2S,3S,4S,5R,6R)-6-[1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
- Carvedilol β-D-glucuronide
- 2-(9H-Carbazol-4-yloxy)-1-[[[2-(2-methoxyphenoxy)ethyl]amino]methyl]ethyl-D-Glucopyranosiduronic Acid
- Carvedilol-D-Glucuronide
- (Glucopyranosiduronic Acid
- Carvedilol b-D-Glucuronide
- 2-(9H-Carbazol-4-yloxy)-1-[[[2-(2-methoxyphenoxy)ethyl]amino]methyl]ethyl b-D-Glucopyranosiduronic Acid
- Carvedilol β-D-Glucuronide (mixture of diasteromers)