122306-11-0
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- CAS號:
- 122306-11-0
- 英文名:
- 1-naphthylacetylspermine
- 英文別名:
- Naspm;C13674;Naspm trihydrochlori;NASPM trihydrochloride;1-naphthylacetylspermine;N-[3-[4-(3-Aminopropylamino)butylamino]propyl]naphthalene-1-acetamide;2-(1-Naphtyl)-N-[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]acetamide;N-[3-[[4-[(3-Aminopropyl)amino]butyl]amino]propyl]-1-naphthaleneacetamide;1-Naphthaleneacetamide, N-[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]-;N-(3-((4-((3-Aminopropyl)amino)butyl)amino)propyl)-2-(naphthalen-1-yl)acetamide
- 中文名:
- 122306-11-0
- 中文別名:
- 1-萘乙酰精胺;化合物 NASPM;化合物 T12187;N-(3-((4-((3-氨基丙基)氨基)丁基)氨基)丙基)-2-(萘-1-基)乙酰胺
- CBNumber:
- CB31315940
- 分子式:
- C22H34N4O
- 分子量:
- 370.53
- MOL File:
- 122306-11-0.mol
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122306-11-0化學性質
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沸點:
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608.9±55.0 °C(Predicted)
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密度:
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1.062±0.06 g/cm3(Predicted)
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儲存條件:
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Desiccate at +4°C
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溶解度:
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DMSO : 10 mg/mL (26.99 mM)
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酸度系數(shù)(pKa):
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15.26±0.46(Predicted)
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形態(tài):
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Liquid
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顏色:
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Colorless to light yellow
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122306-11-0性質、用途與生產工藝
Naspm（1-Naphthyl acetyl spermine）是Joro蜘蛛毒素的合成類似物，是CP-AMPA受體拮抗劑。
NASPM selectively suppresses the inwardly rectifying and Ca
2+
-permeable AMPA receptors expressed in type II neurons. It has no effect on AMPA receptors in type I neurons. At -60 mV, NASPM suppresses AMPA receptors in type II neurons with an IC
50
value of 0.33 μM. The blocking effect of NASPM on the Ca
2+
-permeable AMPA receptors is use and voltage-dependent.
122306-11-0
上下游產品信息
上游原料
下游產品
| 更新日期 | 產品編號 | 產品名稱 | CAS編號 | 包裝 | 價格 |
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| 2025/05/22 | HY-12506A | Naspm trihydrochloride | 122306-11-0 | 1 mg | 363元 |
| 2025/05/22 | HY-12506A | 122306-11-0
Naspm trihydrochloride | 122306-11-0 | 5mg | 800元 |
122306-11-0, 122306-11-0 相關搜索:
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Inhibitors
- Aromatics
- Amines
- 抑制劑
- C22H34N4O
- C22H34N4O3HCl
- 化合物 NASPM
- N-(3-((4-((3-氨基丙基)氨基)丁基)氨基)丙基)-2-(萘-1-基)乙酰胺
- 1-萘乙酰精胺
- 化合物 T12187
- 122306-11-0
- N-(3-((4-((3-Aminopropyl)amino)butyl)amino)propyl)-2-(naphthalen-1-yl)acetamide
- Naspm trihydrochlori
- 1-Naphthaleneacetamide, N-[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]-
- 1-naphthylacetylspermine
- N-[3-[[4-[(3-Aminopropyl)amino]butyl]amino]propyl]-1-naphthaleneacetamidetrihydrochloride
- C13674
- N-[3-[4-(3-Aminopropylamino)butylamino]propyl]naphthalene-1-acetamide
- 2-(1-Naphtyl)-N-[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]acetamide
- NASPM trihydrochloride
- Naspm
- N-[3-[[4-[(3-Aminopropyl)amino]butyl]amino]propyl]-1-naphthaleneacetamide