MD2-TLR4-IN-1
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- CAS號(hào):
- 2249801-12-3
- 英文名:
- MD2-TLR4-IN-1
- 英文別名:
- MD2-TLR4-I;MD2-TLR4-IN-1;MD2-TLR4-IN-1, 10 mM in DMSO;N-(3-(1H-Indol-5-yl)-1H-indazol-5-yl)-2,6-dichlorobenzamide;Benzamide, 2,6-dichloro-N-[3-(1H-indol-5-yl)-1H-indazol-5-yl]-;inhibit,Toll-like Receptor (TLR),MD2 TLR4 IN 1,MD2TLR4IN1,MD-2-TLR4-IN-1,Inhibitor
- 中文名:
- MD2-TLR4-IN-1
- 中文別名:
- 優(yōu)選]MD2-TLR4-IN-1;化合物MD2-TLR4-IN-1;化合物MD2-TLR4-IN-1,10 MM DMSO 溶液;N-(3-(1H-吲哚-5-基)-1H-吲唑-5-基)-2,6-二氯苯甲酰胺
- CBNumber:
- CB25478163
- 分子式:
- C22H14Cl2N4O
- 分子量:
- 421.28
- MOL File:
- 2249801-12-3.mol
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MD2-TLR4-IN-1化學(xué)性質(zhì)
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儲(chǔ)存條件:
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Store at -20°C
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溶解度:
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DMSO: 83.33 mg/mL (197.80 mM)
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形態(tài):
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Solid
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顏色:
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White to off-white
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MD2-TLR4-IN-1性質(zhì)、用途與生產(chǎn)工藝
MD2-TLR4-IN-1 (Compound 22m) 是一種 myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) 的有效抑制劑。MD2-TLR4-IN-1 (compound 22m) 可抑制脂多糖(LPS)誘導(dǎo)的 tumor necrosis factor alpha (TNF-α) 和 interleukin-6 (IL-6) 的表達(dá)，在巨噬細(xì)胞中對(duì)應(yīng)的IC50值分別為0.89 μM和0.53 μM。
| Target | Value |
TLR4
()
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IL-6
(Cell-free assay)
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0.53 μM
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TNF-α
(Cell-free assay)
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0.89 μM
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MD2-TLR4-IN-1
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
| 更新日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS編號(hào) | 包裝 | 價(jià)格 |
|---|
| 2025/05/22 | S0139 | MD2-TLR4-IN-1
MD2-TLR4-IN-1 | 2249801-12-3 | 5mg | 3578.46元 |
| 2025/05/22 | HY-128598 | MD2-TLR4-IN-1
MD2-TLR4-IN-1 | 2249801-12-3 | 100 mg | 7400元 |
2249801-12-3, MD2-TLR4-IN-1 相關(guān)搜索:
- 抑制劑
- 化合物MD2-TLR4-IN-1,10 MM DMSO 溶液
- 優(yōu)選]MD2-TLR4-IN-1
- N-(3-(1H-吲哚-5-基)-1H-吲唑-5-基)-2,6-二氯苯甲酰胺
- 化合物MD2-TLR4-IN-1
- 2249801-12-3
- MD2-TLR4-IN-1, 10 mM in DMSO
- MD2-TLR4-I
- inhibit,Toll-like Receptor (TLR),MD2 TLR4 IN 1,MD2TLR4IN1,MD-2-TLR4-IN-1,Inhibitor
- N-(3-(1H-Indol-5-yl)-1H-indazol-5-yl)-2,6-dichlorobenzamide
- MD2-TLR4-IN-1
- Benzamide, 2,6-dichloro-N-[3-(1H-indol-5-yl)-1H-indazol-5-yl]-