JND3229
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- CAS號:
- 2260886-64-2
- 英文名:
- JND3229
- 英文別名:
- JND3229;JND3229
(JND-3229;JND3229, 10 mM in DMSO;JND3229;JND-3229;JND 3229;N-(trans-4-(3-(2-Chlorophenyl)-7-((3-methyl-4-(4-methylpiperazin-1-yl)phenyl)amino)-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl)cyclohexyl)propionamide;N-[(1r,4r)-4-[3-(2-chlorophenyl)-7-{[3-methyl-4-(4-methylpiperazin-1-yl)phenyl]amino}-2-oxo-1H,2H,3H,4H-[1,3]diazino[4,5-d]pyrimidin-1-yl]cyclohexyl]propanamide;Propanamide, N-[trans-4-[3-(2-chlorophenyl)-3,4-dihydro-7-[[3-methyl-4-(4-methyl-1-piperazinyl)phenyl]amino]-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]cyclohexyl]-
- 中文名:
- JND3229
- 中文別名:
- 化合物JND3229;化合物 T15615;化合物JND3229,10 MM DMSO 溶液;N-(反式-4-(3-(2-氯苯基)-7-((3-甲基-4-(4-甲基哌嗪-1-基)苯基)氨基)-2-氧代-3,4-二氫嘧啶[4,5-D]嘧啶-1(2H)-基)環(huán)己基)丙酰胺
- CBNumber:
- CB24844930
- 分子式:
- C33H41ClN8O2
- 分子量:
- 617.18
- MOL File:
- 2260886-64-2.mol
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JND3229化學(xué)性質(zhì)
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密度:
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1.34±0.1 g/cm3(Predicted)
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儲(chǔ)存條件:
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2-8°C
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溶解度:
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DMSO : 12.5 mg/mL (20.25 mM; Need ultrasonic)
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酸度系數(shù)(pKa):
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16.01±0.40(Predicted)
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形態(tài):
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Solid
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顏色:
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White to light yellow
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JND3229性質(zhì)、用途與生產(chǎn)工藝
JND3229 是一種高效的 EGFRC797S 的第四代可逆抑制劑， IC50 值為 5.8 nM ，同時(shí)對于EGFR L858R/T790M 和 EGFRWT 的 IC50 值分別為 30.5 和 6.8 nM。
JND3229
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
| 更新日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS編號 | 包裝 | 價(jià)格 |
|---|
| 2025/02/08 | HY-119944 | JND3229 | 2260886-64-2 | 1 mg | 440元 |
| 2025/02/08 | HY-119944 | JND3229
JND3229 | 2260886-64-2 | 5mg | 1100元 |
2260886-64-2, JND3229 相關(guān)搜索:
- 抑制劑
- C33H41ClN8O2
- 化合物JND3229,10 MM DMSO 溶液
- 化合物JND3229
- 化合物 T15615
- N-(反式-4-(3-(2-氯苯基)-7-((3-甲基-4-(4-甲基哌嗪-1-基)苯基)氨基)-2-氧代-3,4-二氫嘧啶[4,5-D]嘧啶-1(2H)-基)環(huán)己基)丙酰胺
- 2260886-64-2
- JND3229, 10 mM in DMSO
- N-[(1r,4r)-4-[3-(2-chlorophenyl)-7-{[3-methyl-4-(4-methylpiperazin-1-yl)phenyl]amino}-2-oxo-1H,2H,3H,4H-[1,3]diazino[4,5-d]pyrimidin-1-yl]cyclohexyl]propanamide
- N-(trans-4-(3-(2-Chlorophenyl)-7-((3-methyl-4-(4-methylpiperazin-1-yl)phenyl)amino)-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl)cyclohexyl)propionamide
- Propanamide, N-[trans-4-[3-(2-chlorophenyl)-3,4-dihydro-7-[[3-methyl-4-(4-methyl-1-piperazinyl)phenyl]amino]-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]cyclohexyl]-
- JND3229;JND-3229;JND 3229
- JND3229
(JND-3229
- JND3229