Delafloxacin NEW
Price | $15 | $5 | $1 |
Package | 1kg | 10kg | 50kg |
Min. Order: | 1kg |
Supply Ability: | 500 |
Update Time: | 2024-12-24 |
Product Details
Product Name: Delafloxacin | CAS No.: 189279-58-1 |
Min. Order: 1kg | Purity: 99.9% |
Supply Ability: 500 | Release date: 2024/12/24 |
Cas No. | 189279-58-1 | SDF | Download SDF |
PubChem ID | 487101 | Appearance | Powder |
Formula | C18H12ClF3N4O4 | M.Wt | 440.76 |
Type of Compound | N/A | Storage | Desiccate at -20°C |
Synonyms | RX-3341; WQ-3034; ABT492 | ||
Solubility | DMSO: 25 mg/mL (56.72 mM) | ||
Chemical Name | 1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxoquinoline-3-carboxylic acid | ||
SMILES | C1C(CN1C2=C(C=C3C(=C2Cl)N(C=C(C3=O)C(=O)O)C4=NC(=C(C=C4F)F)N)F)O | ||
Standard InChIKey | DYDCPNMLZGFQTM-UHFFFAOYSA-N | ||
Standard InChI | InChI=1S/C18H12ClF3N4O4/c19-12-13-7(1-9(20)14(12)25-3-6(27)4-25)15(28)8(18(29)30)5-26(13)17-11(22)2-10(21)16(23)24-17/h1-2,5-6,27H,3-4H2,(H2,23,24)(H,29,30) | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. | ||
About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. | ||
Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
Description | Delafloxacin (RX-3341, ABT-492) is a fluoroquinolone antibiotic agent. IC50 Value: MICs ranging from 0.0078 to 0.125 micro g/ml for levofloxacin-resistant Streptococcus pneumoniae strains [1] Target: Antibacterial ABT-492 was more potent against quinolone-susceptible and -resistant gram-positive organisms, had activity similar to that of ciprofloxacin against certain members of the family Enterobacteriaceae, and had comparable activity against quinolone-susceptible, nonfermentative, gram-negative organisms. in vitro: ABT-492 exhibited excellent in vitro activities against all 326 aerobic and anaerobic antral puncture sinus isolates tested with MICs (in micrograms per milliliter) at which 90% of the isolates tested were inhibited as follows: Haemophilus influenzae, 0.001; Moraxella catarrhalis, 0.008; and Streptococcus pneumoniae, 0.015 [2]. ABT-492 was as active as trovafloxacin against Chlamydia trachomatis, indicating good intracellular penetration and antibacterial activity [3]. in vivo: Clinical trial: N/A References: |
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- Since: 2021-09-01
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