4-Chloro-N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide
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- CAS號:
- 1261576-81-1
- 英文名:
- 4-Chloro-N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide
- 英文別名:
- B355252;B355252 >=98% (HPLC);B355252, 10 mM in DMSO;4-chloro-N-(1-naphthalenylmethyl)-5-[3-(1-piperazinyl)phenoxy]-2-thiophenesulfonamide;2-Thiophenesulfonamide, 4-chloro-N-(1-naphthalenylmethyl)-5-[3-(1-piperazinyl)phenoxy]-;4-Chloro-N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide;neurite outgrowth,ischemic neurons,HT22,B355252,glutamate,Inhibitor,Apoptosis,DNA damage,inhibit,B 355252,NGF,LDH level,ROS production,Parkinson disease,phenoxy thiophene sulfonamide,B-355252
- 中文名:
- 4-Chloro-N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide
- 中文別名:
- 化合物B355252;化合物B355252,10 MM DMSO 溶液
- CBNumber:
- CB02750710
- 分子式:
- C25H24ClN3O3S2
- 分子量:
- 514.06
- MOL File:
- 1261576-81-1.mol
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4-Chloro-N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide化學(xué)性質(zhì)
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熔點(diǎn):
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142-144 °C
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沸點(diǎn):
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718.4±70.0 °C(Predicted)
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密度:
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1.370±0.06 g/cm3(Predicted)
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儲存條件:
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-20°C
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溶解度:
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DMSO: soluble10mg/mL, clear
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形態(tài):
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powder
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酸度系數(shù)(pKa):
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10.16±0.50(Predicted)
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顏色:
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white to beige
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4-Chloro-N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide性質(zhì)、用途與生產(chǎn)工藝
B355252 是一種苯氧基噻吩磺酰胺小分子，一種有效的 NGF 受體激動劑。B355252 增強(qiáng) NGF 誘導(dǎo)的神經(jīng)突生長。B355252 通過減輕 DNA 損傷、減少 ROS 產(chǎn)生和 LDH 水平以及防止神經(jīng)元凋亡來保護(hù)缺血性神經(jīng)元免受神經(jīng)元損失。B355252 在谷氨酸誘導(dǎo)的興奮性毒性以及帕金森病 (PD) 的小鼠海馬細(xì)胞系 (HT22) 模型中具有抗凋亡作用。
4-Chloro-N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
| 更新日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS編號 | 包裝 | 價格 |
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| 2023/01/06 | S3428 | 4-Chloro-N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide
B355252 | 1261576-81-1 | 25mg | 10802.6元 |
| 2021/03/30 | S3428 | 4-Chloro-N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide
B355252 | 1261576-81-1 | 5mg | 3595.41元 |
4-Chloro-N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide
生產(chǎn)廠家
1261576-81-1, 4-Chloro-N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide 相關(guān)搜索:
- 抑制劑
- 化合物B355252,10 MM DMSO 溶液
- 化合物B355252
- 1261576-81-1
- B355252, 10 mM in DMSO
- neurite outgrowth,ischemic neurons,HT22,B355252,glutamate,Inhibitor,Apoptosis,DNA damage,inhibit,B 355252,NGF,LDH level,ROS production,Parkinson disease,phenoxy thiophene sulfonamide,B-355252
- 4-chloro-N-(1-naphthalenylmethyl)-5-[3-(1-piperazinyl)phenoxy]-2-thiophenesulfonamide
- B355252 >=98% (HPLC)
- 2-Thiophenesulfonamide, 4-chloro-N-(1-naphthalenylmethyl)-5-[3-(1-piperazinyl)phenoxy]-
- B355252
- 4-Chloro-N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide