98791-67-4
中文名稱
BAY-K-8644 ((R)-(+)-);R-4407;NI-105;(+)-BAY-K-8644
英文名稱
R(+)-BAY K 8644
CAS
98791-67-4
分子式
C16H15F3N2O4
分子量
356.3
MOL 文件
98791-67-4.mol
更新日期
2024/11/15 18:20:32
98791-67-4 結(jié)構(gòu)式
基本信息
中文別名
鈣離子通道抑制劑(BAY-K-8644 ((R)-(+)-)) 英文別名
R-4407NI 105
BAY-r-4407
BAY-k 4407
(+)-BAY-K-8644
R(+)-BAY K 8644
Bay-K-8644 ((R)-(+)-)
R(+)-BAY K 8644 98% 0 C
(+/-)-BAY K 8644, 0 TO 5 °C
(R)(+)BayK8644,(R) (+) Bay K 8644
BAY-K-8644 ((R)-(+)-);R-4407;NI-105;(+)-BAY-K-8644價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2024/11/08 | HY-15125 | BAY-K-8644 ((R)-(+)-);R-4407;NI-105;(+)-BAY-K-8644 (R)-(+)-Bay-K-8644 | 98791-67-4 | 10mM * 1mLin DMSO | 1058元 |
| 2024/11/08 | HY-15125 | BAY-K-8644 ((R)-(+)-);R-4407;NI-105;(+)-BAY-K-8644 (R)-(+)-Bay-K-8644 | 98791-67-4 | 5mg | 1350元 |
| 2024/11/08 | HY-15125 | BAY-K-8644 ((R)-(+)-);R-4407;NI-105;(+)-BAY-K-8644 (R)-(+)-Bay-K-8644 | 98791-67-4 | 10mg | 1800元 |
常見問題列表
生物活性
(R)-(+)-Bay-K-8644 是鈣離子通道抑制劑。(R)-(+)-Bay-K-8644 抑制 Ba2+電流 (IBa)，IC50 為 975 nM。靶點
IC50: 975 nM (I Ba )
體外研究
(R)-(+)-Bay-K-8644, a conventional racemic mixture of Bay K 8644, is widely used as an L-type Ca 2+ channel agonist. Each optical isomer possesses opposite effects on I Ba , (R)-(+)-Bay-K-8644 as an antagonist and S(-)-Bay K 8644 as an agonist. (R)-(+)-Bay-K-8644 inhibits Ba 2+ currents (I Ba ) (IC 50 =975 nM). When (R)-(+)-Bay-K-8644 (0.5 μM) is applied, I Ba is suppressed to 71±10% of control. In the presence of (R)-(+)-Bay-K-8644I Ba . (R)-(+)-Bay-K-8644 is a calcium channel inhibitor.