90880-35-6
中文名稱
神經(jīng)肽-Y (人, 鼠)
英文名稱
NEUROPEPTIDE Y (HUMAN, RAT)
CAS
90880-35-6
分子式
C189H284N55O57RS
分子量
4270.68
MOL 文件
90880-35-6.mol
更新日期
2024/12/22 20:23:45
90880-35-6 結(jié)構(gòu)式
基本信息
中文別名
神經(jīng)肽-Y (人, 鼠) 英文別名
hnpyhNPY, NPY
NPY (HUMAN, RAT)
Neuropeptide Y (rat)
Neuropeptide Y(1-36)
NEUROPEPTIDE Y, HUMAN
NPY FREE ACID (HUMAN, RAT)
NEUROPEPTIDE Y (HUMAN, RAT)
Human neuropeptide Y (29-64)
M.W. 4271.68 C189H285N55O57S
所屬類別
生物化工：多肽物理化學(xué)性質(zhì)
RTECS號QQ4064000
儲存條件−20°C
儲存條件−20°C
溶解度H2O: 1 mg/mL
溶解度H2O：1 mg/mL
形態(tài)powder
顏色white
水溶解性Soluble in water (1.5 mg/ml)
常見問題列表
生物活性
Neuropeptide Y (human) 和阿爾茲海默癥相關(guān)，能夠保護(hù)老鼠皮質(zhì)神經(jīng)元對抗淀粉樣蛋白毒性。體外研究
It is showed that Neuropeptide Y (human) is able to protect cortical neurons from Aβ 25-35 toxicity. 2 μM NPY abolishes the toxic effects of Aβ 25-35 at 24 and 48 h. The same effect on neuronal survival is observed in neurons exposed to 1 μM and 0.5 μM Neuropeptide Y (human) pretreatments. Pretreatment with Neuropeptide Y (29-64), amide, human (TFA) Increases NGF Synthesis, reduces NGF mRNA, and restores NGF release in cortical neurons exposed to Aβ 35-25 .