89845-16-9
中文名稱
Gastrofensin AN 5 free base
英文名稱
Gastrofensin AN 5 free base
CAS
89845-16-9
分子式
C19H21ClN2O2
分子量
344.84
MOL 文件
89845-16-9.mol
89845-16-9 結(jié)構(gòu)式
基本信息
中文別名
化合物 T11367 英文別名
Gastrofensin AN 5 free baseCarbamic acid, [4-(4-chlorophenyl)-1,2,3,4-tetrahydro-2-methyl-8-isoquinolinyl]-, ethyl ester (9CI)
常見問題列表
生物活性
Gastrofensin AN 5 free base 是一種 4-苯基四氫異喹啉衍生物,是一種抗?jié)儎?/span>體內(nèi)研究
Gastrofensin AN 5 supresses the formation of ulcers in all experimental models. From the broad pharmacological studies of Gastrofensin AN 5 on this model it can be seen that even a dose of 0.100 mg/kg has a high antiulcer activity. The increase of the dose leads to a regular increase of the antiulcer activity, the highest suppression of the ulcer index being reaches at a dose of 1 mg/kg (86.15%). The comparative studies with Ranitidine and Cimetidine on the same experimental models of gastric ulcers show that Gastrofensin AN 5 possesses an antiulcer activity many times higher than that of the above-mentioned drugs.