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89105-94-2

中文名稱 FIBRINOGEN-BINDING INHIBITOR PEPTIDE
英文名稱 HIS-HIS-LEU-GLY-GLY-ALA-LYS-GLN-ALA-GLY-ASP-VAL
CAS 89105-94-2
分子式 C50H80N18O16
分子量 1189.28
MOL 文件 89105-94-2.mol
更新日期 2024/12/22 20:23:42
89105-94-2 結(jié)構(gòu)式 89105-94-2 結(jié)構(gòu)式

基本信息

中文別名
HV-12
L-纈氨酸,L-組氨酰-L-組氨酰-L-亮氨酰甘氨酰甘氨酰-L-丙氨酰-L-賴氨酰-L-谷酰
英文別名
HHLGGAKQAGDV
fibrinogen-γ fragment 400-411
FIBRINOGEN Y-CHAIN DODECAPETIDE
FIBRINOGEN-BINDING INHIBITOR PEPTIDE
FIBRINOGEN GAMMA-CHAIN DODECAPEPTIDE
Fibrinogen Binding Inhibitory Peptide
HUMAN FIBRINOGEN-GAMMA FRAGMENT 400-411
HIS-HIS-LEU-GLY-GLY-ALA-LYS-GLN-ALA-GLY-ASP-VAL
Fibrinogen Binding Inhibitor Peptide,HHLGGAKQAGDV
H-HIS-HIS-LEU-GLY-GLY-ALA-LYS-GLN-ALA-GLY-ASP-VAL-OH
所屬類別
生物化工:激動(dòng)劑抑制劑

物理化學(xué)性質(zhì)

沸點(diǎn)1809.9±65.0 °C(Predicted)
密度1.342±0.06 g/cm3(Predicted)
儲(chǔ)存條件−20°C
酸度系數(shù)(pKa)3.20±0.10(Predicted)
形態(tài)Solid
顏色White to off-white
序列H-His-His-Leu-Gly-Gly-Ala-Lys-Gln-Ala-Gly-Asp-Val-OH

安全數(shù)據(jù)

WGK Germany3
纖維蛋白原結(jié)合抑制劑肽價(jià)格(試劑級)
報(bào)價(jià)日期產(chǎn)品編號(hào)產(chǎn)品名稱CAS號(hào)包裝價(jià)格
2024/11/08HY-P1507FIBRINOGEN-BINDING INHIBITOR PEPTIDE
Fibrinogen Binding Inhibitor Peptide
89105-94-21mg800元
2024/11/08HY-P1507FIBRINOGEN-BINDING INHIBITOR PEPTIDE
Fibrinogen Binding Inhibitor Peptide
89105-94-25mg1900元
2024/11/08HY-P1507FIBRINOGEN-BINDING INHIBITOR PEPTIDE
Fibrinogen Binding Inhibitor Peptide
89105-94-210mg3200元

常見問題列表

生物活性
Fibrinogen Binding Inhibitor Peptide 是一種十二肽 (HHLGGAKQAGDV,H12),是纖維蛋白原 γ 鏈羧基末端序列 (γ400-411)。是活化糖蛋白 (GP) IIb/IIIa 配體的特異性結(jié)合位點(diǎn)。
體外研究

Glycoprotein (GP) IIb/IIIa, which exists on the membrane of platelets, changes its form from inactive to active when platelets adhere to collagen exposed on sites of vascular injury. In the circulation, platelet aggregation is mediated by fibrinogen by bridging adjacent platelets through GPIIb/IIIa in an activation-dependent manner. A dodecapeptide HHLGGAKQAGDV (H12), corresponding to the fibrinogen γ-chain carboxy-terminal sequence (γ400-411), is a specific binding site of the ligand for activated GPIIb/IIIa [1].

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