877399-51-4
中文名稱(chēng)
克唑替尼中間體3
英文名稱(chēng)
(R)-tert-butyl 4-(4-(6-aMino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
CAS
877399-51-4
分子式
C26H30Cl2FN5O3
分子量
550.45
MOL 文件
877399-51-4.mol
更新日期
2024/12/03 10:11:12
877399-51-4 結(jié)構(gòu)式
基本信息
中文別名
克唑替尼中間體3克尼唑替尼中間體
((R) - 叔丁基4-(4-(6-氨基-5-(1-(2,6-二氯-3-氟苯基)乙氧基)吡啶-3-基
4-[4-[6-氨基-5-[[?-1-(2,6-二氯-3-氟苯基)乙基]氧基]吡啶-3-基]吡唑-1-基]哌啶-1-羧酸叔丁酯
4-[4-[6-氨基-5-[[(R)-1-(2,6-二氯-3-氟苯基)乙基]氧基]吡啶-3-基]吡唑-1-基]哌啶-1-羧酸叔丁酯
(R)-4-(4-(6-氨基-5-(1-(2,6-二氯-3-氟苯基)乙氧基)吡啶-3-基)-1H-吡唑-1-基)哌啶-1-羧酸叔丁酯
((R)-叔丁基4-(4-(6-氨基-5-(1-(2,6-二氯-3-氟苯基)乙氧基)吡啶-3-基)-1H-吡唑-1-基]基)哌啶-1-羧酸叔丁酯)
英文別名
Crizotinib Impurity 23(R)-tert-butyl 4-(4-(6-aMino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)
tert-butyl 4-[4-[6-amino-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-3-yl]pyrazol-1-yl]piperidine-1-carboxylate
tert-butyl 4-(4-(6-amino-5-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
tert-butyl (R)-4-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
(R)-tert-butyl 4-(4-(6-aMino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
tert-butyl 4-[4-(6-amino-5-{[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethyl]oxy}-3-pyridinyl)-1H-pyrazol-1-yl]-1-piperidinecarboxylate
4-[4-[6-Amino-5-[[(R)-1-(2,6-dichloro-3-fluorophenyl)ethyl]oxy]pyridin-3-yl]pyrazol-1-yl]piperidine-1-carboxylic acid tert-butyl ester
1-Piperidinecarboxylic acid,4-[4-[6-aMino-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-pyridinyl]-1H-pyrazol-1-yl]-, 1,1-diMethylethyl ester
(R)-tert-butyl 4-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridine -3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate (R)-tert-butyl 4-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridine -3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
物理化學(xué)性質(zhì)
熔點(diǎn)150℃
沸點(diǎn)654.7±55.0 °C(Predicted)
密度1.38±0.1 g/cm3(Predicted)
儲(chǔ)存條件Keep in dark place,Inert atmosphere,2-8°C
酸度系數(shù)(pKa)7.11±0.10(Predicted)
