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87096-84-2

中文名稱 GLY-ASN-LEU-TRP-ALA-THR-GLY-HIS-PHE-MET-NH2
英文名稱 NEUROMEDIN B
CAS 87096-84-2
分子式 C52H73N15O12S
分子量 1132.29
MOL 文件 87096-84-2.mol
更新日期 2024/12/22 20:23:43
87096-84-2 結(jié)構(gòu)式 87096-84-2 結(jié)構(gòu)式

基本信息

中文別名
神經(jīng)介素 B
豬神經(jīng)調(diào)節(jié)肽 B
NEUROMEDIN B肽
英文別名
NMB
NEUROMEDIN B
GNLWATGHFM-NH2
Pig neuromedin B
NEUROMEDIN B ≥90%
Porcine neuromedin B
NEUROMEDIN BNEUROMED
NEUROMEDIN B, PORCINE
Neuromedin B, ≥90% (HPLC)
Neuromedin B (pig spinal cord)

物理化學(xué)性質(zhì)

沸點(diǎn)1697.4±65.0 °C(Predicted)
密度1.337±0.06 g/cm3(Predicted)
儲(chǔ)存條件−20°C
儲(chǔ)存條件−20°C
溶解度H2O : 12.5 mg/mL (11.04 mM; Need ultrasonic)
酸度系數(shù)(pKa)13.16±0.46(Predicted)
形態(tài)固體
顏色White to off-white
水溶解性Soluble to 1 mg/ml in water
序列H-Gly-Asn-Leu-Trp-Ala-Thr-Gly-His-Phe-Met-NH2

安全數(shù)據(jù)

WGK Germany3
WGK Germany3
GLY-ASN-LEU-TRP-ALA-THR-GLY-HIS-PHE-MET-NH2價(jià)格(試劑級(jí))
報(bào)價(jià)日期產(chǎn)品編號(hào)產(chǎn)品名稱CAS號(hào)包裝價(jià)格
2024/11/08HY-P0241GLY-ASN-LEU-TRP-ALA-THR-GLY-HIS-PHE-MET-NH2
Neuromedin B
87096-84-21mg800元
2024/11/08HY-P0241GLY-ASN-LEU-TRP-ALA-THR-GLY-HIS-PHE-MET-NH2
Neuromedin B
87096-84-25mg2000元
2024/11/08HY-P0241GLY-ASN-LEU-TRP-ALA-THR-GLY-HIS-PHE-MET-NH2
Neuromedin B
87096-84-210mg3000元

常見問題列表

生物活性
Neuromedin B 是一種含10個(gè)氨基酸的神經(jīng)肽,屬于蛙肽家族,為鈴蟾肽相關(guān)肽。
靶點(diǎn)

Human Endogenous Metabolite

體外研究

Potency to stimulate contraction of rat uterine smooth muscle, that is used as bioassay for isolation of Neuromedin B (NMB), is compared with Bombesin (BN). The relative potency, calculated on molar basis by taking BN as 100, is 48% for GRP and 4.9% for NMB. NMB also has contractile activity on rat stomach strip, but the potency (ratio of peptide concentration required to elicit 50% maximum response; EC 50 ) is only 5% of BN (EC 50 of BN/EC 50 of NMB) and about 10% of GRP (EC 50 of GRP/ EC 50 of NMB).

體內(nèi)研究

Potencies of NMB and GRP for smooth muscle contraction of fundus in wild-type and NMB-R-deficient mice with ED 50 of 14.4±2.3 (n=8) and 10.9±2.3 (n=8) in wild-type mice and NMB-R-deficient mice, respectively.

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