86445-22-9
中文名稱
Auxinole
英文名稱
Auxinole
CAS
86445-22-9
分子式
C20H19NO3
分子量
321.37
MOL 文件
86445-22-9.mol
更新日期
2024/12/06 07:13:28
86445-22-9 結(jié)構(gòu)式
物理化學(xué)性質(zhì)
熔點(diǎn)<170°C (dec.)
儲(chǔ)存條件-20°C Freezer, Under inert atmosphere
溶解度DMSO（微溶）、甲醇（微溶、超聲處理）
形態(tài)固體
顏色灰白色至淺棕色
常見問(wèn)題列表
生物活性
Auxinole 是一種有效的 TIR1/AFB 受體植物激素拮抗劑，能夠與 TIR1 結(jié)合，阻止 TIR1-IAA-Aux/IAA 復(fù)合物的形成，從而抑制 auxin 應(yīng)答基因的表達(dá)。靶點(diǎn)
TIR1/AFB receptor
體外研究
Auxinole is a potent auxin antagonist of TIR1/AFB receptors, and binds TIR1 to block the formation of the TIR1-IAA-Aux/IAA complex and then inhibits auxin-responsive gene expression. In addition, Auxinole competitively inhibits various auxin responses in planta. Auxinole causes reduction in IAA-triggered depolarization in root hair cells. Auxinole (20?μM) also represses the transient increase in [Ca 2+ ] cyt completely, and blocks Ca 2+ response.