787623-60-3
787623-60-3 結(jié)構(gòu)式
物理化學(xué)性質(zhì)
沸點(diǎn)480.0±45.0 °C(Predicted)
密度1.168±0.06 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度溶于二甲基亞砜
酸度系數(shù)(pKa)15.67±0.40(Predicted)
形態(tài)Solid
顏色Light yellow to yellow
常見問題列表
生物活性
(Rac)-E1R (Compound 2) 是 E1R 的外消旋體。(Rac)-E1R 是 sigma-1 受體的正變構(gòu)調(diào)節(jié)劑 (Sig1R PAM)，可用于認(rèn)知和記憶障礙的研究。體外研究
Sigma-1 receptor plays an important role in neuronal plasticity, a process implicated in the pathophysiology of neuropsychiatric diseases, such as Alzheimer’s disease, major depressive disorders, and schizophrenia.