778274-97-8
中文名稱
NULL
英文名稱
N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide
CAS
778274-97-8
分子式
C20H17F3N4O3
分子量
418.37
MOL 文件
778274-97-8.mol
更新日期
2023/02/22 11:54:00
778274-97-8 結(jié)構(gòu)式
基本信息
中文別名
化合物MULTI-KINASE INHIBITOR I 英文別名
MDK74978MDK74978
MDK-74978
Multi-kinase inhibitor 1
Multi-kinase inhibitor I
MDK74978(Multi-kinase inhibitor)
MDK 74978. Multi-kinase inhibitor I
MDK74978
MDK-74978
MDK 74978. MULTI-KINASE INHIBITOR I
N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide
Benzamide, N-(2-hydroxyethyl)-4-[6-[[4-(trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]-
所屬類別
生物化工：激動劑抑制劑常見問題列表
生物活性
Multi-kinase inhibitor 1 是一種有效的多激酶 (multi-kinase) 抑制劑。Multi-kinase inhibitor 1 有用于導(dǎo)致與酪氨酸激酶活性異?；蚴Э赜嘘P(guān)的疾病或失調(diào)的潛力，特別是與 PDGF-R，c-Kit 和 Bcr-abl 活性相關(guān)的疾病。靶點(diǎn)
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PDGFR
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Bcr-Abl
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體外研究
Multi-kinase inhibitor 1 (compound 68) is a potent multi-kinase inhibitor. The protein kinases represent a large family of proteins, which play a central role in the regulation of a wide variety of cellular processes and maintaining control over cellular function. These kinases include receptor tyrosine kinases, such as platelet derived growth factor receptor kinase(PDGF-R), the receptor kinase for stem cell factor, c-Kit, and non-receptor tyrosine kinases, such as the fusion kinase Bcr-abl.